248282-10-2

• 常用中文名：5-氯-1,2-二氢-4-羟基-1-甲基-2-氧代-3-喹啉羧酸乙酯
• 常用英文名：ETHYL-5-CHLORO-1,2-DIHYDRO-4-HYDROXY-1-METHYL-2-OXO-3-QUINOLINE CARBOXYLATE
• CAS号：248282-10-2
• 分子式：C₁₃H₁₂ClNO₄
• 分子量：281.69200
• 发布时间：2018-12-22 21:31:28
• 更新时间：2024-01-08 13:32:16

名称

• 中文名: 5-氯-1,2-二氢-4-羟基-1-甲基-2-氧代-3-喹啉羧酸乙酯
• 英文名: ethyl 5-chloro-4-hydroxy-1-methyl-2-oxoquinoline-3-carboxylate
• 英文别名: ETHYL-5-CHLORO-1,2-DIHYDRO-4-HYDROXY-1-METHYL-2-OXO-3-QUINOLINE CARBOXYLATE; 1,2-dihydro-4-hydroxy-5-chloro-1-methyl-2-oxo-quinoline-3-carboxylic acid ethyl ester; 5-chloro-1,2-dihydro-4-hydroxy-1-methyl-2-oxo-3-quinolinecarboxylic acid ethyl ester; ethyl 5-chloro-4-hydroxy-1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylate; 3-Quinolinecarboxylicacid,5-chloro-1,2-dihydro-4-hydroxy-1-methyl-2-oxo-,ethyl ester

物化性质

• 密度: 1.436g/cm3
• 沸点: 419ºC at 760mmHg
• 分子式: C₁₃H₁₂ClNO₄
• 分子量: 281.69200
• 闪点: 207.2ºC
• 精确质量: 281.04500
• PSA: 68.53000
• LogP: 2.07420
• 蒸汽压: 9.03E-08mmHg at 25°C
• 折射率: 1.615

合成路线

40707-01-5 105-53-3 ~22% 248282-10-2

文献：Tomassoli, Isabelle; Ismaili, Lhassane; Pudlo, Marc; De Los Rios, Cristobal; Soriano, Elena; Colmena, Ines; Gandia, Luis; Rivas, Luis; Samadi, Abdelouahid; Marco-Contelles, Jose; Refouvelet, Bernard European Journal of Medicinal Chemistry, 2011 , vol. 46, # 1 p. 1 - 10

118-48-9 105-53-3 74-88-4 ~73% 248282-10-2

文献：Active Biotech AB Patent: US6133285 A1, 2000 ;

20829-96-3 105-53-3 74-88-4 ~% 248282-10-2

文献：Active Biotech AB Patent: EP1095021 B1, 2003 ; Location in patent: Page/Page column 6 ;

20829-96-3 ~% 248282-10-2

文献：Joensson, Stig; Andersson, Gunnar; Fex, Tomas; Fristedt, Tomas; Hedlund, Gunnar; Jansson, Karl; Abramo, Lisbeth; Fritzson, Ingela; Pekarski, Olga; Runstroem, Anna; Sandin, Helena; Thuvesson, Ingela; Bjoerk, Anders Journal of Medicinal Chemistry, 2004 , vol. 47, # 8 p. 2075 - 2088

2148-56-3 ~% 248282-10-2

文献：Joensson, Stig; Andersson, Gunnar; Fex, Tomas; Fristedt, Tomas; Hedlund, Gunnar; Jansson, Karl; Abramo, Lisbeth; Fritzson, Ingela; Pekarski, Olga; Runstroem, Anna; Sandin, Helena; Thuvesson, Ingela; Bjoerk, Anders Journal of Medicinal Chemistry, 2004 , vol. 47, # 8 p. 2075 - 2088

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