5633-16-9

• 常用中文名：利奥吡咯
• 常用英文名：Leiophrrole
• CAS号：5633-16-9
• 分子式：C₂₃H₂₈N₂O
• 分子量：348.48100
• 发布时间：2018-06-22 16:30:06
• 更新时间：2023-01-23 15:42:26

名称

• 中文名: 利奥吡咯
• 英文名: N,N-diethyl-2-[2-(2-methyl-5-phenylpyrrol-1-yl)phenoxy]ethanamine
• 英文别名: 1-[2-(2-Diaethylamino-aethoxy)-phenyl]-2-methyl-5-phenyl-pyrrol; 1-(2-<2-Diethylamino-ethoxy>-phenyl)-2-methyl-5-phenyl-pyrrol; Leiopyrrole; Pyrrole,1-(o-(2-(diethylamino)ethoxy)phenyl)-2-methyl-5-phenyl; Leiopirrol [INN-Spanish]; Ethanamine,N,N-diethyl-2-(2-(2-methyl-5-phenyl-1H-pyrrol-1-yl)phenoxy); Leiopirrol; Leiopyrrolum [INN-Latin]; 1-(o-(2-(Diethylamino)ethoxy)phenyl)-2-methyl-5-phenylpyrrole; 2-Methyl-5-phenyl-1-<2-(2-diethylamino-ethoxy)-phenyl>-pyrrol; 1-[2-(2-diethylamino-ethoxy)-phenyl]-2-methyl-5-phenyl-pyrrole; DV 714; Leioplegil

物化性质

• 密度: 1.01g/cm3
• 沸点: 497.9ºC at 760mmHg
• 分子式: C₂₃H₂₈N₂O
• 分子量: 348.48100
• 闪点: 254.9ºC
• 精确质量: 348.22000
• PSA: 17.40000
• LogP: 5.17330
• 折射率: 1.552

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UX9465050 CHEMICAL NAME : Pyrrole, 1-(o-(2-(diethylamino)ethoxy)phenyl)-2-methyl-5-pheny l- CAS REGISTRY NUMBER : 5633-16-9 BEILSTEIN REFERENCE NO. : 0300657 LAST UPDATED : 199612 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C23-H28-N2-O MOLECULAR WEIGHT : 348.53 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 700 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AAREAV Anesthesie, Analgesie, Reanimation. (Paris, France) V.14-38, 1957-81. Volume(issue)/page/year: 20,371,1963 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 180 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AAREAV Anesthesie, Analgesie, Reanimation. (Paris, France) V.14-38, 1957-81. Volume(issue)/page/year: 20,371,1963 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 475 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AAREAV Anesthesie, Analgesie, Reanimation. (Paris, France) V.14-38, 1957-81. Volume(issue)/page/year: 20,371,1963 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 115 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AAREAV Anesthesie, Analgesie, Reanimation. (Paris, France) V.14-38, 1957-81. Volume(issue)/page/year: 20,371,1963

合成路线

95-55-6 ~% 5633-16-9

文献：Buu-Hoi et al. Journal of Medicinal and Pharmaceutical Chemistry, 1959 , vol. 1, p. 23,26

583-05-1 ~% 5633-16-9

文献：Buu-Hoi et al. Journal of Medicinal and Pharmaceutical Chemistry, 1959 , vol. 1, p. 23,26

93315-44-7 100-35-6 ~% 5633-16-9

文献：Buu-Hoi et al. Journal of Medicinal and Pharmaceutical Chemistry, 1959 , vol. 1, p. 23,26

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