52112-66-0

• 常用中文名：2-氨基-6-溴苯并恶唑
• 常用英文名：6-Bromo-1,3-benzoxazol-2-amine
• CAS号：52112-66-0
• 分子式：C₇H₅BrN₂O
• 分子量：213.031
• 发布时间：2018-07-01 19:47:10
• 更新时间：2024-01-03 13:59:09

名称

• 中文名: 2-氨基-6-溴苯并恶唑
• 英文名: 6-bromo-1,3-benzoxazol-2-amine
• 中文别名: 2-氨基-6-溴苯并噁唑
• 英文别名: 2-Benzoxazolamine, 6-bromo-; 6-bromobenzo[d]oxazol-2-amine; 2-Amino-6-bromobenzoxazole; 2-Benzoxazolamine,6-bromo; 6-bromo-benzoxazol-2-ylamine; 6-Bromo-1,3-benzoxazol-2-amine; 6-bromo-benzooxazol-2-ylamine; 6-Brom-benzoxazol-2-ylamin; BENZOXAZOLE,2-AMINO-6-BROMO; 6-bromo-2-Benzoxazolamine

物化性质

• 密度: 1.8±0.1 g/cm3
• 沸点: 340.4±34.0 °C at 760 mmHg
• 分子式: C₇H₅BrN₂O
• 分子量: 213.031
• 闪点: 159.7±25.7 °C
• 精确质量: 211.958511
• PSA: 52.05000
• LogP: 2.64
• 蒸汽压: 0.0±0.7 mmHg at 25°C
• 折射率: 1.716
• 储存条件: 室温，密封，干燥

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DM4530000 CHEMICAL NAME : Benzoxazole, 2-amino-6-bromo- CAS REGISTRY NUMBER : 52112-66-0 BEILSTEIN REFERENCE NO. : 0127765 LAST UPDATED : 199712 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C7-H5-Br-N2-O MOLECULAR WEIGHT : 213.05 WISWESSER LINE NOTATION : T56 BN DOJ CZ GE HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : MDCHAG Medicinal Chemistry: A Series of Monographs. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1963- Volume(issue)/page/year: 4(1),338,1964 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 200 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : MDCHAG Medicinal Chemistry: A Series of Monographs. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1963- Volume(issue)/page/year: 4(1),338,1964 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 560 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : MDCHAG Medicinal Chemistry: A Series of Monographs. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1963- Volume(issue)/page/year: 4(1),336,1964 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 294 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : MDCHAG Medicinal Chemistry: A Series of Monographs. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1963- Volume(issue)/page/year: 4(1),336,1964

安全

• 危害码 (欧洲): Xn
• 海关编码: 2934999090

合成路线

1967-25-5 ~% 52112-66-0

文献：Chikhale, Rupesh V.; Pant, Amit M.; Menghani, Sunil S.; Wadibhasme, Pankaj G.; Khedekar, Pramod B. South African Journal of Chemistry, 2013 , vol. 66, p. 254 - 262

4570-41-6 ~62% 52112-66-0

文献：Stec, Markian M.; Andrews, Kristin L.; Booker, Shon K.; Caenepeel, Sean; Freeman, Daniel J.; Jiang, Jian; Liao, Hongyu; McCarter, John; Mullady, Erin L.; San Miguel, Tisha; Subramanian, Raju; Tamayo, Nuria; Wang, Ling; Yang, Kevin; Zalameda, Leeanne P.; Zhang, Nancy; Hughes, Paul E.; Norman, Mark H. Journal of Medicinal Chemistry, 2011 , vol. 54, # 14 p. 5174 - 5184

1404480-07-4 ~% 52112-66-0

文献：INTELLIKINE, INC.; REN, Pingda; LIU, Yi; LI, Liansheng; CHAN, Katrina; WILSON, Troy, Edward Patent: WO2010/51042 A1, 2010 ; Location in patent: Page/Page column 134 ;

1520-26-9 ~% 52112-66-0

文献：Desai et al. Journal of the Chemical Society, 1934 , p. 1186,1190

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%