119695-82-8

• 常用中文名：1-(2-异丙基苯基)哌嗪
• 常用英文名：1-(2-propan-2-ylphenyl)piperazine
• CAS号：119695-82-8
• 分子式：C₁₃H₂₀N₂
• 分子量：204.31100
• 发布时间：2018-09-18 11:22:50
• 更新时间：2024-01-10 12:31:13

名称

• 中文名: 1-(2-异丙基苯基)哌嗪
• 英文名: 1-(2-propan-2-ylphenyl)piperazine

物化性质

• 分子式: C₁₃H₂₀N₂
• 分子量: 204.31100
• 精确质量: 204.16300
• PSA: 15.27000
• LogP: 2.61340

合成路线

1311383-41-1 ~93% 119695-82-8

文献：AGIOS PHARMACEUTICALS, INC.; SALITURO, Francesco, G.; SAUNDERS, Jeffrey, O. Patent: WO2011/72174 A1, 2011 ; Location in patent: Page/Page column 116 ; WO 2011/072174 A1

821-48-7 643-28-7 71-36-3 ~% 119695-82-8

文献：McNeilab, Inc. Patent: US4992441 A1, 1991 ;

110-85-0 7073-94-1 ~% 119695-82-8

文献：Richardson, Timothy I.; Ornstein, Paul L.; Briner, Karin; Fisher, Matthew J.; Backer, Ryan T.; Biggers, C. Kelly; Clay, Michael P.; Emmerson, Paul J.; Hertel, Larry W.; Hsiung, Hansen M.; Husain, Saba; Kahl, Steven D.; Lee, Jonathan A.; Lindstrom, Terry D.; Martinelli, Michael J.; Mayer, John P.; Mullaney, Jeffery T.; O'Brien, Thomas P.; Pawlak, Joseph M.; Revell, Kevin D.; Shah, Jikesh; Zgombick, John M.; Herr, R. Jason; Melekhov, Alex; Sampson, Peter B.; King, Chi-Hsin R. Journal of Medicinal Chemistry, 2004 , vol. 47, # 3 p. 744 - 755

7073-94-1 ~% 119695-82-8

文献：AGIOS PHARMACEUTICALS, INC.; SALITURO, Francesco, G.; SAUNDERS, Jeffrey, O. Patent: WO2011/72174 A1, 2011 ; WO 2011/072174 A1

821-48-7 643-28-7 ~60% 119695-82-8

文献：Konstantinova, Igor; Bukhryakov, Konstantin; Gezentsvey, Yuri; Krasavin, Mikhail Letters in Organic Chemistry, 2011 , vol. 8, # 9 p. 628 - 630

643-28-7 ~% 119695-82-8

文献：Jia, Jian-Min; Liu, Fang; Xu, Xiao-Li; Guo, Xiao-Ke; Jiang, Fen; Cherfaoui, Bahidja; Sun, Hao-Peng; You, Qi-Dong Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 6 p. 1557 - 1561

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