76-42-6

• 常用中文名：羟可待酮
• 常用英文名：oxycodone
• CAS号：76-42-6
• 分子式：C₁₈H₂₁NO₄
• 分子量：315.364
• 相关类别： 分析化学 标准品 标准物质
• 发布时间：2018-06-12 18:37:09
• 更新时间：2024-01-04 18:23:51

名称

• 中文名: 羟可待酮
• 英文名: oxycodone
• 中文别名: 羟考酮; 二氢羟基可待因酮
• 英文别名: Thecodine; Tekodin; Oxycodon; (5α)-14-hydroxy-17-methyl-3-(methyloxy)-4,5-epoxymorphinan-6-one; 14-hydroxy-dihydrocodeinone; Oxycon; Oxikon; Eubine; oxanest; (1S,5R,13R,17S)-17-hydroxy-10-methoxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0.0.0]octadeca-7(18),8,10-trien-14-one; Eucodalum; Eukodal; oxycodone; Oxicon; (-)-14-Hydroxydihydrocodeinone; Dihydrone; percocet; (1S,5R,13R,17S)-17-Hydroxy-10-methoxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0.0.0]octadeca-7(18),8,10-trien-14-on; Tecodin; Thekodin; Percodan; Oxicone; Morphinan-6-one, 4,5α-epoxy-14-hydroxy-3-methoxy-17-methyl-; (1S,5R,13R,17S)-17-hydroxy-10-méthoxy-4-méthyl-12-oxa-4-azapentacyclo[9.6.1.0.0.0]octadéca-7(18),8,10-trién-14-one; Morphinan-6-one, 4,5-epoxy-14-hydroxy-3-methoxy-17-methyl-, (5α)-; Morphinan-6-one,4,5-epoxy-14-hydroxy-3-methoxy-17-methyl-, (5a)-; Eutagen; (5α)-14-Hydroxy-3-methoxy-17-methyl-4,5-epoxymorphinan-6-one; 14-Hydroxydihydrocodeinone; Dihydrohydroxycodeinone; (5a)-4,5-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one; endone; EINECS 200-960-2

物化性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 501.6±50.0 °C at 760 mmHg
• 熔点: 218-220°
• 分子式: C₁₈H₂₁NO₄
• 分子量: 315.364
• 闪点: 257.1±30.1 °C
• 精确质量: 315.147064
• PSA: 59.00000
• LogP: 1.67
• 蒸汽压: 0.0±1.4 mmHg at 25°C
• 折射率: 1.659
• 储存条件: 2-8°C

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : QD2450000 CHEMICAL NAME : Morphinan-6-one, 4,5-alpha-epoxy-14-hydroxy-3-methoxy-17-methyl- CAS REGISTRY NUMBER : 76-42-6 BEILSTEIN REFERENCE NO. : 0043446 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C18-H21-N-O4 MOLECULAR WEIGHT : 315.40 WISWESSER LINE NOTATION : T B6566 B6/CO 4ABBC R BX FV HO PN GHT&&TTJ CQ JO1 P1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 320 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 3,261,1961 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 426 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 28ZNAE "Public Health Reports, Supplement." (Washington, DC) Volume(issue)/page/year: 138,27,1938

安全

• 符号: GHS07
• 信号词: Warning
• 危害声明: H302
• 警示性声明: P301 + P312 + P330
• 危害码 (欧洲): F,T
• 风险声明 (欧洲): 11-23/24/25-39/23/24/25
• 安全声明 (欧洲): 7-16-36/37-45
• 危险品运输编码: UN 1544
• 包装等级: II
• 危险类别: 6.1(a)

合成路线

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