22440-93-3

• 常用中文名：1,3-双(二甲基氨基)苯
• 常用英文名：N,N,N',N'-tetramethylbenzene-1,3-diamine
• CAS号：22440-93-3
• 分子式：C₁₀H₁₆N₂
• 分子量：164.24700
• 发布时间：2017-04-06 11:00:53
• 更新时间：2024-01-06 20:05:38
• 下载msds

名称

• 中文名: 1,3-双(二甲胺基)苯
• 英文名: N,N,N′,N′- Tetramethyl-1,3-phenylenediamine
• 英文别名: 1-N,1-N,3-N,3-N-tetramethylbenzene-1,3-diamine

物化性质

• 密度: 0.992g/cm3
• 沸点: 270.5ºC at 760mmHg
• 分子式: C₁₀H₁₆N₂
• 分子量: 164.24700
• 闪点: 110.9ºC
• 精确质量: 164.13100
• PSA: 6.48000
• LogP: 1.81860
• 蒸汽压: 0.00682mmHg at 25°C
• 折射率: 1.577
• 储存条件: 2-8°C，密闭，干燥

MSDS

SECTION 1: Identification of the substance/mixture and of the company/undertaking Product identifiers : N,N,N′,N′- Tetramethyl-1,3-phenylenediamine Product name REACH No.: A registration number is not available for this substance as the substance or its uses are exempted from registration, the annual tonnage does not require a registration or the registration is envisaged for a later registration deadline. CAS-No.: 22440-93-3 SECTION 2: Hazards identification Classification of the substance or mixture Classification according to Regulation (EC) No 1272/2008 Acute toxicity, Oral (Category 3), H301 Skin irritation (Category 2), H315 Eye irritation (Category 2), H319 Skin sensitisation (Category 1), H317 Specific target organ toxicity - single exposure (Category 3), H335 For the full text of the H-Statements mentioned in this Section, see Section 16. Classification according to EU Directives 67/548/EEC or 1999/45/EC T ToxicR25, R36/37/38, R43, R52 For the full text of the R-phrases mentioned in this Section, see Section 16. Label elements Labelling according Regulation (EC) No 1272/2008 Pictogram Signal wordDanger Hazard statement(s) Toxic if swallowed. Causes skin irritation. May cause an allergic skin reaction. Causes serious eye irritation. May cause respiratory irritation. Precautionary statement(s) Avoid breathing vapours. Wear protective gloves. P301 + P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/ physician. P305 + P351 + P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Supplemental Hazardnone Statements Other hazards - none SECTION 3: Composition/information on ingredients Substances Synonyms: 1,3-Bis(dimethylamino)benzene N,N,N`,N`-Tetramethyl-m-phenylenediamine Formula: C10H16N2 Molecular Weight: 164,25 g/mol CAS-No.: 22440-93-3 EC-No.: 244-998-8 Hazardous ingredients according to Regulation (EC) No 1272/2008 ComponentClassificationConcentration N,N,N`,N`-Tetramethyl-1,3-phenylenediamine CAS-No.22440-93-3Acute Tox. 3; Skin Irrit. 2; Eye <= 100 % EC-No.244-998-8Irrit. 2; Skin Sens. 1; STOT SE 3; H301, H315, H317, H319, Hazardous ingredients according to Directive 1999/45/EC ComponentClassificationConcentration N,N,N`,N`-Tetramethyl-1,3-phenylenediamine CAS-No.22440-93-3T, R25 - R36/37/38 - R43 -<= 100 % EC-No.244-998-8R52 For the full text of the H-Statements and R-Phrases mentioned in this Section, see Section 16 SECTION 4: First aid measures Description of first aid measures General advice Consult a physician. Show this safety data sheet to the doctor in attendance. If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician. In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician. Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11 Indication of any immediate medical attention and special treatment needed no data available SECTION 5: Firefighting measures Extinguishing media Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Special hazards arising from the substance or mixture no data available Advice for firefighters Wear self contained breathing apparatus for fire fighting if necessary. Further information no data available SECTION 6: Accidental release measures Personal precautions, protective equipment and emergency procedures Wear respiratory protection. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. For personal protection see section 8. Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. Methods and materials for containment and cleaning up Soak up with inert absorbent material and dispose of as hazardous waste. Keep in suitable, closed containers for disposal. Reference to other sections For disposal see section 13. SECTION 7: Handling and storage Precautions for safe handling Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. For precautions see section 2.2. Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Specific end use(s) A part from the uses mentioned in section 1.2 no other specific uses are stipulated SECTION 8: Exposure controls/personal protection Control parameters Components with workplace control parameters Exposure controls Appropriate engineering controls Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling the product. Personal protective equipment Eye/face protection Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Body Protection Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Control of environmental exposure Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. SECTION 9: Physical and chemical properties Information on basic physical and chemical properties a) AppearanceForm: liquid b) Odourno data available c) Odour Thresholdno data available d) pHno data available e) Melting point/freezingno data available point f) Initial boiling point andno data available boiling range g) Flash point> 110 °C h) Evapouration rateno data available i) Flammability (solid, gas) no data available j) Upper/lowerno data available flammability or explosive limits k) Vapour pressureno data available l) Vapour densityno data available m) Relative density0,976 g/cm3 at 25 °C n) Water solubilityno data available o) Partition coefficient: n- log Pow: 2,843 octanol/water p) Auto-ignitionno data available temperature q) Decompositionno data available temperature r) Viscosityno data available s) Explosive propertiesno data available t) Oxidizing propertiesno data available Other safety information no data available SECTION 10: Stability and reactivity Reactivity no data available Chemical stability Stable under recommended storage conditions. Possibility of hazardous reactions no data available Conditions to avoid no data available Incompatible materials Acids, Acid chlorides, Acid anhydrides, Chloroformates, Strong oxidizing agents Hazardous decomposition products Other decomposition products - no data available In the event of fire: see section 5 SECTION 11: Toxicological information Information on toxicological effects Acute toxicity no data available Skin corrosion/irritation no data available Serious eye damage/eye irritation no data available Respiratory or skin sensitisation no data available Germ cell mutagenicity no data available Carcinogenicity IARC:No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC. Reproductive toxicity no data available Specific target organ toxicity - single exposure no data available Specific target organ toxicity - repeated exposure no data available Aspiration hazard no data available Additional Information RTECS: Not available Absorption into the body leads to the formation of methemoglobin which in sufficient concentration causes cyanosis. Onset may be delayed 2 to 4 hours or longer., To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. SECTION 12: Ecological information Toxicity no data available Persistence and degradability no data available Bioaccumulative potential no data available Mobility in soil no data available Results of PBT and vPvB assessment PBT/vPvB assessment not available as chemical safety assessment not required/not conducted Other adverse effects Harmful to aquatic life. no data available SECTION 13: Disposal considerations Waste treatment methods Product Offer surplus and non-recyclable solutions to a licensed disposal company. Contaminated packaging Dispose of as unused product. SECTION 14: Transport information UN number ADR/RID: 2811IMDG: 2811IATA: 2811 UN proper shipping name ADR/RID: TOXIC SOLID, ORGANIC, N.O.S. (N,N,N`,N`-Tetramethyl-1,3-phenylenediamine) IMDG: TOXIC SOLID, ORGANIC, N.O.S. (N,N,N`,N`-Tetramethyl-1,3-phenylenediamine) IATA:Toxic solid, organic, n.o.s. (N,N,N`,N`-Tetramethyl-1,3-phenylenediamine) Transport hazard class(es) ADR/RID: 6.1IMDG: 6.1IATA: 6.1 Packaging group ADR/RID: IIIIMDG: IIIIATA: III Environmental hazards ADR/RID: noIMDG Marine pollutant: noIATA: no Special precautions for user no data available SECTION 15: Regulatory information This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006. Safety, health and environmental regulations/legislation specific for the substance or mixture no data available Chemical Safety Assessment For this product a chemical safety assessment was not carried out SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 符号: GHS06
• 信号词: Danger
• 危害声明: H301-H315-H317-H319-H335
• 警示性声明: P261-P280-P301 + P310-P305 + P351 + P338
• 危害码 (欧洲): T
• 危险品运输编码: UN 2811 6.1 / PGIII

合成路线

124-40-3 541-73-1 ~94% 22440-93-3

文献：Han, Chong; Buchwald, Stephen L. Journal of the American Chemical Society, 2009 , vol. 131, p. 7532 - 7533

67-56-1 108-45-2 ~% 22440-93-3

文献：Wurster; Morley Chemische Berichte, 1879 , vol. 12, p. 1814

67-56-1 ~% 22440-93-3

文献：Pinnow Chemische Berichte, 1899 , vol. 32, p. 1405 Full Text Show Details Pinnow; Wegner Chemische Berichte, 1897 , vol. 30, p. 3111

512-56-1 108-45-2 ~% 22440-93-3

文献：Friedmann,G. et al. Bulletin de la Societe Chimique de France, 1970 , p. 706 - 711

7647-01-0 67-56-1 108-45-2 ~% 22440-93-3

文献：Romburgh Recueil des Travaux Chimiques des Pays-Bas, 1888 , vol. 7, p. 1 Full Text Show Details Wurster; Morley Chemische Berichte, 1879 , vol. 12, p. 1814

60-29-7 578-57-4 ~% 15799-79-8 700-75-4 详细

文献：Benkeser; DeBoer Journal of Organic Chemistry, 1956 , vol. 21, p. 281,283

上下游产品

上游产品  8
124-40-3 541-73-1 67-56-1 108-45-2
512-56-1 7647-01-0 60-29-7 578-57-4
下游产品  4
99-07-0 108-46-3 71639-08-2 52695-14-4