132-65-0

• 常用中文名：二苯并噻吩
• 常用英文名：Dibenzothiophene
• CAS号：132-65-0
• 分子式：C₁₂H₈S
• 分子量：184.257
• 相关类别： 化学试剂 有机试剂 三环化合物
• 发布时间：2018-02-03 08:00:00
• 更新时间：2024-01-02 10:49:25
• Dibenzothiophene是一种有机合成中间体, 由两个苯环稠合到一个中心噻吩环。

名称

• 中文名: 二苯并噻吩
• 英文名: dibenzothiophene
• 中文别名: 二苯并噻吩/硫芴; 二苯噻吩
• 英文别名: 9-Thiafluorene; Dibenzo(b,d)thiophene; MFCD00004969; Diphenylene Sulfide; a-thiafluorene; 2,2'-Biphenylylene sulfide; Diphenylenesulfide; [1,1'-Biphenyl]-2,2'-diyl sulfide; EINECS 205-072-9; Dibenzothiophene; DBT,Diphenylene sulfide; dibenzo[b,d]thiophene

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 332-333 ºC
• 熔点: 97-100 °C(lit.)
• 分子式: C₁₂H₈S
• 分子量: 184.257
• 闪点: 170 ºC
• 精确质量: 184.034668
• PSA: 28.24000
• LogP: 4.38
• 外观性状: 黄色至绿色固体
• 蒸汽压: 0.0±0.7 mmHg at 25°C
• 折射率: 1.756
• 储存条件:

  贮存

  密封于阴凉处保存

• 稳定性:

  基本性质

  无色或白色针状结晶。易溶于乙醇、苯，溶于水、乙醚。熔点97～100℃。沸点332～333℃ 。

• 水溶解性: SOLUBLE
• 分子结构:

  五、分子性质数据：

  1、 摩尔折射率：60.32

  2、 摩尔体积（m³/mol）：147.1

  3、 等张比容（90.2K）：398.0

  4、 表面张力（3.0 dyne/cm）：53.5

  5、 极化率（0.5 10 ^-24cm ³）：23.91

• 计算化学:

  1.疏水参数计算参考值（XlogP）:无

  2.氢键供体数量:0

  3.氢键受体数量:1

  4.可旋转化学键数量:0

  5.互变异构体数量:无

  6.拓扑分子极性表面积28.2

  7.重原子数量:13

  8.表面电荷:0

  9.复杂度:170

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

生物活性

• 描述: Dibenzothiophene是一种有机合成中间体, 由两个苯环稠合到一个中心噻吩环。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 其他

MSDS

Name: Dibenzothiophene 99% Material Safety Data Sheet Synonym: 2,2'-Biphenylylene sulfide; 9-Thiafluorene; Dibenzo(b,d)thiophene; Diphenylene sulfide CAS: 132-65-0 Section 1 - Chemical Product MSDS Name:Dibenzothiophene 99% Material Safety Data Sheet Synonym:2,2'-Biphenylylene sulfide; 9-Thiafluorene; Dibenzo(b,d)thiophene; Diphenylene sulfide Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 132-65-0 Dibenzothiophene 99 205-072-9 Hazard Symbols: XN Risk Phrases: 22 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Harmful if swallowed. Potential Health Effects Eye: May cause eye irritation. Skin: May cause skin irritation. Ingestion: Harmful if swallowed. Causes gastrointestinal irritation with nausea, vomiting and diarrhea. Inhalation: May cause respiratory tract irritation. Chronic: Chronic ingestion may cause liver damage. Section 4 - FIRST AID MEASURES Eyes: In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical aid. Skin: In case of contact, flush skin with plenty of water. Remove contaminated clothing and shoes. Get medical aid if irritation develops and persists. Wash clothing before reuse. Ingestion: If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical aid. Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. This material in sufficient quantity and reduced particle size is capable of creating a dust explosion. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Avoid generating dusty conditions. Provide ventilation. Section 7 - HANDLING and STORAGE Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Avoid breathing dust. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 132-65-0: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Crystalline powder Color: yellow to green Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: 332 - 333 deg C @ 760 mm Hg Freezing/Melting Point: 97 - 100 deg C Autoignition Temperature: > 450 deg C (> 842.00 deg F) Flash Point: 170 deg C ( 338.00 deg F) Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: soluble Specific Gravity/Density: Molecular Formula: C12H8S Molecular Weight: 184.26 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Dust generation. Incompatibilities with Other Materials: Strong oxidizing agents. Hazardous Decomposition Products: Carbon monoxide, oxides of sulfur, carbon dioxide. Hazardous Polymerization: Has not been reported. Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 132-65-0: HQ3490550 LD50/LC50: CAS# 132-65-0: Oral, mouse: LD50 = 470 mg/kg. Carcinogenicity: Dibenzothiophene - Not listed by ACGIH, IARC, or NTP. Other: See actual entry in RTECS for complete information. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Not regulated as a hazardous material. IMO Not regulated as a hazardous material. RID/ADR Shipping Name: Not regulated. Hazard Class: UN Number: Packing group: Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XN Risk Phrases: R 22 Harmful if swallowed. Safety Phrases: WGK (Water Danger/Protection) CAS# 132-65-0: No information available. Canada CAS# 132-65-0 is listed on Canada's DSL List. CAS# 132-65-0 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 132-65-0 is listed on the TSCA inventory. SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

毒理学数据: 急性毒性数据： 小鼠经口LD50：470mg/kg 小鼠腹腔LD：>500mg/kg 其他多剂量数据： 大鼠经口TDLo：7480mg/kg/24W-I CHEMICAL IDENTIFICATION RTECS NUMBER : HQ3490550 CHEMICAL NAME : Dibenzothiophene CAS REGISTRY NUMBER : 132-65-0 LAST UPDATED : 199710 DATA ITEMS CITED : 7 MOLECULAR FORMULA : C12-H8-S HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 470 mg/kg TOXIC EFFECTS : Behavioral - general anesthetic Behavioral - coma REFERENCE : FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 12,787,1989 TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 4,378,1952 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 7480 mg/kg/24W-I TOXIC EFFECTS : Liver - fatty liver degeneration Liver - changes in liver weight Endocrine - changes in spleen weight REFERENCE : FOREAE Food Research. (Champaign, IL) V.1-25, 1936-60. For publisher information, see JFDSAZ. Volume(issue)/page/year: 7,161,1942 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4832 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 28 (estimated)

安全

• 符号: GHS07, GHS09
• 信号词: Warning
• 危害声明: H302-H410
• 警示性声明: P273-P501
• 个人防护装备: dust mask type N95 (US);Eyeshields;Faceshields;Gloves
• 危害码 (欧洲): Xn:Harmful;
• 风险声明 (欧洲): R22
• 安全声明 (欧洲): S36
• 危险品运输编码: 2811
• WGK德国: 3
• RTECS号: HQ3490550
• 包装等级: III
• 危险类别: 9
• 海关编码: 29349990

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海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
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