80937-23-1

• 常用中文名：(E)-4-(3,4-二甲氧基苯基)-4-氧代-2-丁烯酸乙酯
• 常用英文名：(E)Ethyl 4-(3,4-dimethoxyphenyl)-4-oxo-2-butenoate
• CAS号：80937-23-1
• 分子式：C₁₄H₁₆O₅
• 分子量：264.27400
• 发布时间：2018-12-04 10:39:39
• 更新时间：2024-01-09 18:55:29
• 【用途一】
  用作医药中间体

名称

• 中文名: (E)-4-(3,4-二甲氧基苯基)-4-氧代-2-丁烯酸乙酯
• 英文名: (E)-Ethyl 4-(3,4-dimethoxyphenyl)-4-oxo-2-butenoate
• 中文别名: (E)4-(3,4-二甲氧基苯基)-4-氧-2-丁烯酸乙酯; 4-(3,4-二氧基苯基)-4-氧丁烯酸乙酯; (E)4-二甲氧基苯基-4-氧-2-丁烯酸乙酯
• 英文别名: (E)Ethyl4-(3,4-dimethoxyphenyl; 3-(3,4-dimethoxybenzoyl)acrylic acid; (E)4-(3,4-dimethyoxyphenyl)-4-oxo-2-butenoate; 4-(3,4-dimethoxyphenyl)-4-oxocrotonic acid; 4-(3,4-dimethoxyphenyl)-4-oxo-2-butenoic acid; (E)-4-(3,4-dimethoxyphenyl)-4-oxocrotonic acid ethyl aster; MFCD08458864; (E)-4-(3,4-Dimethoxyphenyl)-4-oxo-2-butenoic acid; Ethyl 4-(3,4-dimethoxyphenyl)-4-oxycrotonate; 4-Oxo-4-(3.4-dimethoxy-phenyl)-trans-crotonsaeure; VAC; (E)Ethyl 4-(3,4-dimethoxyphenyl)-4-oxo-2-butenoate (VAC); (E)ETHYL 4-(3,4-DIMETHOXYPHENYL)-4-OXO-2-BUTENOATE; (E)-ethyl 4-(3,4-dimethoxyphenyl)-4-oxobut-2-enoate; 4-oxo-4-(3.4-dimethoxy-phenyl)-trans-crotonic acid; EINECS 279-631-0

物化性质

• 密度: 1.138g/cm3
• 沸点: 393.2ºC at 760 mmHg
• 熔点: 87.0-91.0ºC
• 分子式: C₁₄H₁₆O₅
• 分子量: 264.27400
• 闪点: 208.2ºC
• 精确质量: 264.10000
• PSA: 61.83000
• LogP: 2.00580
• 折射率: 1.515

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : EM9140000 CHEMICAL NAME : 2-Butenoic acid, 4-(3,4-dimethoxyphenyl)-4-oxo-, (E)- CAS REGISTRY NUMBER : 80937-23-1 BEILSTEIN REFERENCE NO. : 3137849 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C12-H12-O5 MOLECULAR WEIGHT : 236.24 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FRXXBL French Demande Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2481118

安全

• 海关编码: 2918990090

合成路线

108-31-6 91-16-7 ~61% 80937-23-1

文献：Sankio Chemical Co., Ltd.; Meiji Seika Kaisha, Ltd. Patent: EP1505054 A1, 2005 ; Location in patent: Page/Page column 9-11 ;

89781-43-1 ~% 80937-23-1

文献：EP1505054 A1, ; Page/Page column 24 ;

108-31-6 91-16-7 ~29% 80937-23-1 86690-98-4

文献：Chemistry Letters, , vol. 35, # 1 p. 22 - 23

91-16-7 ~% 80937-23-1

文献：US4594197 A1, ;

1131-62-0 563-96-2 ~47% 80937-23-1

文献：Bianchi, Mario; Butti, Alina; Christidis, Yani; Perronnet, Jacques; Barzaghi, Fernando; et al. European Journal of Medicinal Chemistry, 1988 , vol. 23, p. 45 - 52

上下游产品

上游产品  5
108-31-6 91-16-7 89781-43-1 1131-62-0
563-96-2
下游产品  0

海关

海关编码	2918990090
中文概述	2918990090. 其他含其他附加含氧基羧酸（包括酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%