480450-89-3

• 常用中文名：5-氯-4-氟-1H-吲哚-2-羧酸甲酯
• 常用英文名：Methyl 5-chloro-4-fluoro-1H-indole-2-carboxylate
• CAS号：480450-89-3
• 分子式：C₁₀H₇ClFNO₂
• 分子量：227.620
• 发布时间：2019-01-24 12:42:00
• 更新时间：2024-01-04 21:36:26

名称

• 中文名: 5-氯-4-氟-1H-吲哚-2-羧酸甲酯
• 英文名: Methyl 5-chloro-4-fluoro-1H-indole-2-carboxylate
• 英文别名: methyl 5-chloro-4-fluoroindole-2-carboxylate; Methyl 5-chloro-4-fluoro-1H-indole-2-carboxylate; 1H-Indole-2-carboxylic acid, 5-chloro-4-fluoro-, methyl ester; 5-chloro-4-fluoroindole-2-carboxylic acid methyl ester

物化性质

• 密度: 1.5±0.1 g/cm3
• 沸点: 371.3±37.0 °C at 760 mmHg
• 分子式: C₁₀H₇ClFNO₂
• 分子量: 227.620
• 闪点: 178.4±26.5 °C
• 精确质量: 227.014938
• PSA: 42.09000
• LogP: 3.52
• 蒸汽压: 0.0±0.8 mmHg at 25°C
• 折射率: 1.626
• 储存条件: 室温

合成路线

67-56-1 ~69% 480450-89-3

文献：IDENIX PHARMACEUTICALS, INC. Patent: WO2008/42240 A2, 2008 ; Location in patent: Page/Page column 112; 116-117 ;

480450-90-6 ~% 480450-89-3

文献：DAIICHI PHARMACEUTICAL CO., LTD. Patent: EP1577301 A1, 2005 ; Location in patent: Page/Page column 207-208 ;

1816-92-8 85070-48-0 ~% 480450-89-3 480450-90-6

文献：DAIICHI PHARMACEUTICAL CO., LTD. Patent: US2005/20645 A1, 2005 ;

67-56-1 186446-26-4 ~74% 480450-89-3

文献：Mayes, Benjamin A.; Chaudhuri, Narayan C.; Hencken, Christopher P.; Jeannot, Frederic; Latham, G. Mark; Mathieu, Steven; Mcgarry, F. Patrick; Stewart, Alistair J.; Wang, Jingyang; Moussa, Adel Organic Process Research and Development, 2010 , vol. 14, # 5 p. 1248 - 1253

869299-68-3 ~% 480450-89-3

文献：Mayes, Benjamin A.; Chaudhuri, Narayan C.; Hencken, Christopher P.; Jeannot, Frederic; Latham, G. Mark; Mathieu, Steven; Mcgarry, F. Patrick; Stewart, Alistair J.; Wang, Jingyang; Moussa, Adel Organic Process Research and Development, 2010 , vol. 14, # 5 p. 1248 - 1253

367-22-6 ~% 480450-89-3

文献：Mayes, Benjamin A.; Chaudhuri, Narayan C.; Hencken, Christopher P.; Jeannot, Frederic; Latham, G. Mark; Mathieu, Steven; Mcgarry, F. Patrick; Stewart, Alistair J.; Wang, Jingyang; Moussa, Adel Organic Process Research and Development, 2010 , vol. 14, # 5 p. 1248 - 1253

1018450-35-5 ~% 480450-89-3

文献：Mayes, Benjamin A.; Chaudhuri, Narayan C.; Hencken, Christopher P.; Jeannot, Frederic; Latham, G. Mark; Mathieu, Steven; Mcgarry, F. Patrick; Stewart, Alistair J.; Wang, Jingyang; Moussa, Adel Organic Process Research and Development, 2010 , vol. 14, # 5 p. 1248 - 1253

1018450-37-7 ~% 480450-89-3

文献：Mayes, Benjamin A.; Chaudhuri, Narayan C.; Hencken, Christopher P.; Jeannot, Frederic; Latham, G. Mark; Mathieu, Steven; Mcgarry, F. Patrick; Stewart, Alistair J.; Wang, Jingyang; Moussa, Adel Organic Process Research and Development, 2010 , vol. 14, # 5 p. 1248 - 1253

上下游产品

上游产品  7
67-56-1 1816-92-8 85070-48-0 186446-26-4
869299-68-3 367-22-6 1018450-37-7
下游产品  1
186446-26-4