55300-29-3

• 常用中文名：安曲非宁
• 常用英文名：antrafenine
• CAS号：55300-29-3
• 分子式：C₃₀H₂₆F₆N₄O₂
• 分子量：588.544
• 发布时间：2018-07-13 16:31:12
• 更新时间：2024-01-06 05:52:39

名称

• 中文名: 安曲非宁
• 英文名: 2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]ethyl 2-[[7-(trifluoromethyl)quinolin-4-yl]amino]benzoate
• 英文别名: Benzoic acid, 2-[[7-(trifluoromethyl)-4-quinolinyl]amino]-, 2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl ester; 2-[4-(a,a,a-trifluoro-m-tolyl)-1-piperazinyl]ethyl-n-(7-trifluoromethyl-4-quinolyl)anthranilate; Antrafeninum [INN-Latin]; 4-(3-Trifluoromethyl)phenylpiperazineethanol o-(7-trifluoromethyl-4-quinolylamino)benzoate; 2-{4-[3-(Trifluoromethyl)phenyl]piperazin-1-yl}ethyl 2-{[7-(trifluoromethyl)quinolin-4-yl]amino}benzoate; SL 73-033; Stakan; antrafenine; Benzoic acid,2-((7-(trifluoromethyl)-4-quinolinyl)amino)-,2-(4-(3-(trifluoromethyl)phenyl)-1-piperazinyl)ethyl ester; Stakane; Antrafenino [INN-Spanish]; 2-{4-[3-(Trifluoromethyl)phenyl]-1-piperazinyl}ethyl 2-{[7-(trifluoromethyl)-4-quinolinyl]amino}benzoate; 2-[[7-(Trifluoromethyl)-4-quinolinyl]amino]benzoic Acid 2-[4-[3-(Trifluoromethyl)phenyl]-1-piperazinyl]ethyl Ester; 2-(7-trifluoromethyl-quinolin-4-ylamino)-benzoic acid 2-[4-(3-trifluoromethyl-phenyl)-piperazin-1-yl]-ethyl ester

物化性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 648.0±55.0 °C at 760 mmHg
• 分子式: C₃₀H₂₆F₆N₄O₂
• 分子量: 588.544
• 闪点: 345.7±31.5 °C
• 精确质量: 588.195984
• PSA: 57.70000
• LogP: 9.06
• 蒸汽压: 0.0±1.9 mmHg at 25°C
• 折射率: 1.589

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TM0806000 CHEMICAL NAME : Piperazineethanol, 4-(alpha,alpha,alpha-trifluoro-m-tolyl)-, N-(7-trifluoromethyl-4- quinolyl)anthranilate CAS REGISTRY NUMBER : 55300-29-3 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C30-H26-F6-N4-O2 MOLECULAR WEIGHT : 588.60 WISWESSER LINE NOTATION : T66 BNJ IXFFF EMR BVO2- AT6N DNTJ DR CXFFF HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 4 gm/kg TOXIC EFFECTS : Behavioral - analgesia REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 22,554,1979