351457-86-8

• 常用中文名：5-溴-3-甲酰基-4-甲基吡啶
• 常用英文名：5-Bromo-4-methylnicotinaldehyde
• CAS号：351457-86-8
• 分子式：C₇H₆BrNO
• 分子量：200.033
• 发布时间：2018-12-29 14:16:53
• 更新时间：2024-02-16 10:24:50

名称

• 中文名: 5-溴-3-甲酰基-4-甲基吡啶
• 英文名: 5-bromo-4-methylpyridine-3-carbaldehyde
• 英文别名: 3-bromo-4-methyl-5-formyl pyridine; 3-Pyridinecarboxaldehyde, 5-bromo-4-methyl-; 5-Bromo-4-methylnicotinaldehyde; 5-Bromo-4-methyl-pyridine-3-carbaldehyde

物化性质

• 密度: 1.6±0.1 g/cm3
• 沸点: 275.6±35.0 °C at 760 mmHg
• 分子式: C₇H₆BrNO
• 分子量: 200.033
• 闪点: 120.5±25.9 °C
• 精确质量: 198.963272
• PSA: 29.96000
• LogP: 2.15
• 蒸汽压: 0.0±0.6 mmHg at 25°C
• 折射率: 1.604
• 储存条件: 2-8°C，惰性气体氛围

安全

• 危害码 (欧洲): Xi

合成路线

3430-23-7 68-12-2 ~71% 351457-86-8

文献：PFIZER INC., Patent: WO2006/54151 A1, 2006 ; Location in patent: Page/Page column 8 ;

68-12-2 ~% 351457-86-8

文献：SANOFI-AVENTIS Patent: US2006/4000 A1, 2006 ; Location in patent: Page/Page column 15 ;

69321-60-4 68-12-2 ~% 351457-86-8

文献：NOVARTIS AG; ASTEX THERAPEUTICS LIMITED; HOWARD, Steven; MORTENSON, Paul Neil; HISCOCK, Steven Douglas; WOOLFORD, Alison Jo-Anne; WOODHEAD, Andrew James; CHESSARI, Gianni; O'REILLY, Marc; CONGREVE, Miles Stuart; DAGOSTIN, Claudio; CHO, Young Shin; YANG, Fan; CHEN, Christine Hiu-Tung; BRAIN, Christopher Thomas; LAGU, Bharat; WANG, Yaping; KIM, Sunkyu; GRIALDES, John; LUZZIO, Michael Joseph; PEREZ, Lawrence Blas Patent: WO2010/125402 A1, 2010 ; Location in patent: Page/Page column 121-122 ; WO 2010/125402 A1

109-72-8 3430-23-7 ~% 351457-86-8

文献：EPITHERIX, LLC Patent: US2011/34441 A1, 2011 ;

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351458-17-8