1604-14-4

• 常用中文名：2,6-二氯-异烟酸乙酯
• 常用英文名：Ethyl 2,6-dichloroisonicotinate
• CAS号：1604-14-4
• 分子式：C₈H₇Cl₂NO₂
• 分子量：220.05300
• 相关类别： 医药中间体 杂环化合物 吡啶类化合物 吡啶衍生物
• 发布时间：2018-06-07 16:47:30
• 更新时间：2024-01-09 10:10:58

名称

• 中文名: 2,6-二氯异烟酸乙酯
• 英文名: 2,6-Dichloro-isonicotinic acid ethyl ester
• 英文别名: ethyl 2,6-dichloropyridine-4-carboxylate

物化性质

• 密度: 1.367g/cm3
• 沸点: 311.4ºC at 760mmHg
• 分子式: C₈H₇Cl₂NO₂
• 分子量: 220.05300
• 闪点: 142.2ºC
• 精确质量: 218.98500
• PSA: 39.19000
• LogP: 2.56510
• 蒸汽压: 0.000564mmHg at 25°C
• 折射率: 1.54
• 储存条件: 2-8°C，保存于惰性气体中

安全

• 海关编码: 2933399090

合成路线

75308-46-2 64-17-5 ~% 1604-14-4

文献：ACTELION PHARMACEUTICALS LTD Patent: WO2009/24905 A1, 2009 ; Location in patent: Page/Page column 51 ; WO 2009/024905 A1

101990-72-1 ~% 1604-14-4

文献：Ciba-Geigy Corporation Patent: US4968344 A1, 1990 ;

7664-93-9 5398-44-7 ~% 1604-14-4

文献：The Wellcome Foundation Limited Patent: US5202356 A1, 1993 ;

125850-02-4 623-47-2 ~0% 1604-14-4 58584-86-4

文献：Meerpoel; Deroover; Van Aken; Lux; Hoornaert Synthesis, 1991 , # 9 p. 765 - 768

99-11-6 ~% 1604-14-4

文献：Abdel Salam, Osama I.; Khalifa, Nagy M.; Said, Said A.; Amr, Abd El-Galil E. Research on Chemical Intermediates, 2014 , vol. 40, # 3 p. 1147 - 1155

64-17-5 5398-44-7 ~83% 1604-14-4

文献：Kumar, Rohan J.; Karlsson, Susanne; Streich, Daniel; Jensen, Alice Rolandini; Jaeger, Michael; Becker, Hans-Christian; Bergquist, Jonas; Johansson, Olof; Hammarstroem, Leif Chemistry - A European Journal, 2010 , vol. 16, # 9 p. 2830 - 2842

64-17-5 42521-08-4 ~93% 1604-14-4

文献：Phillips, Gary; Guilford, William J.; Buckman, Brad O.; Davey, David D.; Eagen, Keith A.; Koovakkat, Sunil; Liang, Amy; McCarrick, Meg; Mohan, Raju; Ng, Howard P.; Pinkerton, Michael; Subramanyam, Babu; Ho, Elena; Trinh, Lan; Whitlow, Marc; Wu, Shung; Xu, Wei; Morrissey, Michael M. Journal of Medicinal Chemistry, 2002 , vol. 45, # 12 p. 2484 - 2493

海关

海关编码	2933399090
中文概述	2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%