2165-19-7

• 常用中文名：胍生
• 常用英文名：Guanoxan
• CAS号：2165-19-7
• 分子式：C₁₀H₁₃N₃O₂
• 分子量：207.22900
• 相关类别： 原料药 循环系统用药 抗高血压病药
• 发布时间：2018-06-17 16:58:39
• 更新时间：2024-01-10 18:46:46

名称

• 中文名: 胍生
• 英文名: 2-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)guanidine
• 英文别名: 2-Guanidinmethyl-2,3-dihydro-benzo<1,4>dioxin; Envacar; 2-Guanidinomethyl-2,3-dihydro-benzo-<1,4>dioxin; Guanoxane; Guanoxon; Guanoxan; debrisoquin

物化性质

• 密度: 1.4g/cm3
• 沸点: 389.9ºC at 760mmHg
• 熔点: 164-165°
• 分子式: C₁₀H₁₃N₃O₂
• 分子量: 207.22900
• 闪点: 189.6ºC
• 精确质量: 207.10100
• PSA: 80.36000
• LogP: 1.50040
• 蒸汽压: 2.75E-06mmHg at 25°C
• 折射率: 1.639

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : ME8510200 CHEMICAL NAME : Guanidine, (1,4-benzodioxan-2-ylmethyl)- CAS REGISTRY NUMBER : 2165-19-7 BEILSTEIN REFERENCE NO. : 1251616 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C10-H13-N3-O2 MOLECULAR WEIGHT : 207.26 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human - man DOSE/DURATION : 208 mg/kg/1Y TOXIC EFFECTS : Skin and Appendages - dermatitis, other (after systemic exposure) REFERENCE : 34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969 Volume(issue)/page/year: -,296,1969

合成路线

1094-91-3 ~% 2165-19-7

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 17 p. 2377 - 2380

128318-80-9 ~% 2165-19-7

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 17 p. 2377 - 2380

3663-82-9 ~% 2165-19-7

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 17 p. 2377 - 2380

247226-20-6 ~% 2165-19-7

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 17 p. 2377 - 2380

4442-59-5 ~% 2165-19-7

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 17 p. 2377 - 2380

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