81703-55-1

• 常用中文名：环丙炔(钙盐)
• 常用英文名：U 61431F
• CAS号：81703-55-1
• 分子式：C₄₄H₇₀CaO₈
• 分子量：767.100
• 发布时间：2018-06-19 07:46:21
• 更新时间：2024-01-06 18:07:43
• Ciprostene is the 9β-methyl analog of carbaprostacyclin and a stable analog of PGI2.

名称

• 中文名: 环丙炔(钙盐)
• 英文名: 6,9alpha-methylene-9beta-methyl-11alpha,15s-dihydroxy-prosta-5z,13e-dien-1-oic acid, calcium salt
• 英文别名: ciprostene calcium; ciprostene calcium salt; U 61431F; Calcium bis{(5Z)-5-[(3aS,5R,6R,6aR)-5-hydroxy-6-[(1E,3S)-3-hydroxy-1-octen-1-yl]-3a-methylhexahydro-2(1H)-pentalenylidene]pentanoate}; (3aS-(2Z,3aa,5b,6a(1E,3R*),6aa))-5-(Hexahydro-5-hydroxy-6-(3-hydroxy-1-octenyl)-3a-methyl-2(1H)-pentalenylidene)pentanoic Acid Calcium Salt (2:1); 9-b-Methylcarbacyclin; 9-β-Methylcarbacyclin; Calcium (Z)-(3aS,5R,6R,6aR)-Hexahydro-5-hydroxy-6-((E)-(3S)-3-hydroxy-1-octenyl)-3a-methyl-D2(1H),d-pentalenevalerate (1:2); calcium bis{(5Z)-5-[(3aS,5R,6R,6aR)-5-hydroxy-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-3a-methylhexahydropentalen-2(1H)-ylidene]pentanoate}; Pentanoic acid, 5-[(3aS,5R,6R,6aR)-hexahydro-5-hydroxy-6-[(1E,3S)-3-hydroxy-1-octen-1-yl]-3a-methyl-2(1H)-pentalenylidene]-, calcium salt, (5Z)- (2:1)

物化性质

• 沸点: 514.3ºC at 760 mmHg
• 分子式: C₄₄H₇₀CaO₈
• 分子量: 767.100
• 闪点: 278.9ºC
• 精确质量: 766.469666
• PSA: 133.52000
• LogP: 8.77020
• 储存条件: -20°C，密闭，干燥

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : SA3696000 CAS REGISTRY NUMBER : 81703-55-1 LAST UPDATED : 199512 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C44-H70-O8.Ca MOLECULAR WEIGHT : 767.22 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 30200 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CDREEA Cardiovascular Drug Reviews. (Raven Press, 1185 Avenue of the Americas, New York, NY 10036) V.6- 1988- Volume(issue)/page/year: 10,233,1992 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 48800 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CDREEA Cardiovascular Drug Reviews. (Raven Press, 1185 Avenue of the Americas, New York, NY 10036) V.6- 1988- Volume(issue)/page/year: 10,233,1992

合成路线

81845-44-5 ~80% 81703-55-1

文献：Aristoff, Paul A.; Johnson, Paul D.; Harrison, Allen W. Journal of Organic Chemistry, 1983 , vol. 48, # 26 p. 5341 - 5348

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