97043-05-5

• 常用中文名：N-((Vinyloxy)carbonyl)deacetylthiocolchicine
• 常用英文名：N-((Vinyloxy)carbonyl)deacetylthiocolchicine
• CAS号：97043-05-5
• 分子式：C₂₃H₂₅NO₆S
• 分子量：443.51300
• 发布时间：2016-11-26 00:02:27
• 更新时间：2024-01-27 19:14:58

名称

• 英文名: Carbamic acid, [5,6,7,9-tetrahydro-1,2,3-trimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-7-yl]-, ethenyl ester, (S)
• 英文别名: 1-<(trimethylsilyl)methyl>-2-pyridone; N-trimethylsilylmethyl-2-pyridone; N-<(vinyloxy)carbonyl>deacetylthiocolchicine; 2(1H)-Pyridinone,1-[(trimethylsilyl)methyl]; N-[(trimethylsilyl)methyl]pyridone

物化性质

• 密度: 1.29g/cm3
• 沸点: 677.9ºC at 760 mmHg
• 分子式: C₂₃H₂₅NO₆S
• 分子量: 443.51300
• 闪点: 363.8ºC
• 精确质量: 443.14000
• PSA: 108.39000
• LogP: 4.70940
• 折射率: 1.609

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DF9290000 CHEMICAL NAME : Benzo(a)heptalene-7-carbamic acid, 5,6,7,9-tetrahydro-10-(methylthio)-9-oxo-1,2,3- trimethoxy-, vinyl ester CAS REGISTRY NUMBER : 97043-05-5 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C23-H25-N-O6-S MOLECULAR WEIGHT : 443.55 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 87500 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 28,1204,1985

合成路线

5130-24-5 2731-16-0 ~53% 97043-05-5

文献：Kerekes, Peter; Sharma, Padam N.; Brossi, Arnold; Chignell, Colin F.; Quinn, Frank R. Journal of Medicinal Chemistry, 1985 , vol. 28, # 9 p. 1204 - 1208

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