中文名 | 4-(Boc-氨基)四氢吡喃-4-羧酸 |
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英文名 | 4-N-BOC-Amino-4-carboxytetrahydropyran |
中文别名 |
4-(Boc-氨基)四氢吡喃-4-甲酸
4-N-boc-氨基-4-羰基四氢噻喃 4-BOC-氨基四氢吡喃-4-甲酸盐酸盐 4-(叔丁氧羰基-氨基)四氢吡喃-4-羧酸 |
英文别名 |
4-[(tert-Butoxycarbonyl)amino]tetrahydro-2H-pyran-4-carboxylic acid
2H-Pyran-4-carboxylic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]tetrahydro- 4-({[(2-Methyl-2-propanyl)oxy]carbonyl}amino)tetrahydro-2H-pyran-4-carboxylic acid 4-(Boc-amino)tetrahydropyran-4-carboxylic acid 4-[(2-methylpropan-2-yl)oxycarbonylamino]oxane-4-carboxylic acid 4-N-Boc-Amino-4-carboxytetrahydropyran MFCD02683136 |
密度 | 1.2±0.1 g/cm3 |
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沸点 | 407.9±45.0 °C at 760 mmHg |
分子式 | C11H19NO5 |
分子量 | 245.272 |
闪点 | 200.5±28.7 °C |
精确质量 | 245.126328 |
PSA | 84.86000 |
LogP | 0.99 |
蒸汽压 | 0.0±2.0 mmHg at 25°C |
折射率 | 1.497 |
储存条件 | 保存方法:密闭,阴凉,干燥处 |
稳定性 | 避氧化物 |
计算化学 | 1、 疏水参数计算参考值(XlogP):1.4 2、 氢键供体数量:1 3、 氢键受体数量:5 4、 可旋转化学键数量:3 5、 变异构体数量:2 6、 拓扑分子极性表面积(TPSA):87.7 7、 重原子数量:17 8、 表面电荷:-1 9、 复杂度:296 10、同位素原子数量:0 11、确定原子立构中心数量:0 12、不确定原子立构中心数量:0 13、确定化学键立构中心数量:0 14、不确定化学键立构中心数量:0 15、共价键单元数量:1 |
更多 | 1. 性状:白色或奶油色的晶体粉末 2. 密度(g/mL25 ºC):未确定 3. 相对蒸汽密度(g/mL,空气=1)未确定 4. 熔点(ºC):未确定 5. 沸点(ºC,常压):未确定 6. 沸点(ºC15mmHg):未确定 7. 折射率:未确定 8. 闪点(ºF):未确定 9. 比旋光度(º):未确定 10. 自燃点或引燃温度(ºC):未确定 11. 蒸气压(kPa,25ºC):未确定 12. 饱和蒸气压(kPa,60ºC):未确定 13. 燃烧热(KJ/mol):未确定 14. 临界温度(ºC):未确定 15. 临界压力(KPa):未确定 16. 油水(辛醇/水)分配系数的对数值:未确定 17. 爆炸上限(%,V/V):未确定 18. 爆炸下限(%,V/V):未确定 19. 溶解性:未确定 |
Synonym:4-N-(tert-Butoxycarbonyl)-Amino-4-Carboxytetrahydropyran Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: 36/37/38 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin. Potential Health Effects Eye: Causes eye irritation. May cause chemical conjunctivitis. Skin: Causes skin irritation. Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. Inhalation: Causes respiratory tract irritation. Can produce delayed pulmonary edema. Chronic: Effects may be delayed. Section 4 - FIRST AID MEASURES Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Ingestion: Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth resuscitation. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or appropriate foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions. Provide ventilation. Section 7 - HANDLING and STORAGE Handling: Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Wash clothing before reuse. Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 172843-97-9: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: white Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: Not available. Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C11H19NO5 Molecular Weight: 245.27 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable at room temperature in closed containers under normal storage and handling conditions. Conditions to Avoid: Incompatible materials, dust generation, excess heat. Incompatibilities with Other Materials: Oxidizing agents. Hazardous Decomposition Products: Carbon monoxide, oxides of nitrogen, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 172843-97-9 unlisted. LD50/LC50: Not available. Carcinogenicity: 4-N-BOC-Amino-4-Carboxytetrahydropyran - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA No information available. IMO No information available. RID/ADR No information available. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XI Risk Phrases: R 36/37/38 Irritating to eyes, respiratory system and skin. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 Wear suitable gloves and eye/face protection. WGK (Water Danger/Protection) CAS# 172843-97-9: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 172843-97-9 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 172843-97-9 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A |
生态学数据: 1、其它有害作用:通常对水是稍微危害的,若无政府许可,勿将材料排入周围环境。
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危害码 (欧洲) | Xi:Irritant; |
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风险声明 (欧洲) | R36/37/38 |
安全声明 (欧洲) | S26-S37/39 |
海关编码 | 2932999099 |
上游产品 4 | |
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下游产品 0 |
海关编码 | 2932999099 |
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中文概述 | 2932999099. 其他仅含氧杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0% |
申报要素 | 品名, 成分含量, 用途 |
Summary | 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |