中文名 | 1-(4-甲苯基)哌嗪二盐酸盐 |
---|---|
英文名 | 1-(p-Tolyl)piperazine dihydrochloride |
中文别名 |
1-(对-甲苯基)哌嗪二盐酸盐
1-(对甲苯)哌嗪双盐酸盐 |
英文别名 |
1-(p-tolyl)piperazine dihydrochloride
MFCD00035286 EINECS 235-975-3 |
沸点 | 321.2ºC at 760mmHg |
---|---|
熔点 | 214ºC |
分子式 | C11H18Cl2N2 |
分子量 | 249.18000 |
闪点 | 153.8ºC |
精确质量 | 248.08500 |
PSA | 15.27000 |
LogP | 3.40240 |
蒸汽压 | 0.000303mmHg at 25°C |
储存条件 | 常温密闭,阴凉通风干燥 |
稳定性 | 常温常压下稳定 避免的物料 氧化物 水分/潮湿 |
分子结构 | 1、 摩尔折射率:54.63 2、 摩尔体积(m3/mol):174.0 3、 等张比容(90.2K):427.2 4、 表面张力(dyne/cm):36.3 5、 极化率(10-24cm3):21.65 |
计算化学 | 1、 氢键供体数量:3 2、 氢键受体数量:2 3、 可旋转化学键数量:1 4、 拓扑分子极性表面积(TPSA):15.3 5、 重原子数量:15 6、 表面电荷:0 7、 复杂度:144 8、 同位素原子数量:0 9、 确定原子立构中心数量: 0 10、 不确定原子立构中心数量:0 11、 确定化学键立构中心数量:0 12、 不确定化学键立构中心数量:0 13、 共价键单元数量:3 |
更多 | 1. 性状:暗红色固体 2. 密度( g/mL, 25 ℃ ):未确定
3. 相对蒸汽密度(g/mL,空气=1):未确定 4. 熔点(ºC):237-241 5. 沸点(ºC,常压):未确定 6. 沸点(ºC,10mmHg):未确定 7. 折射率:未确定 8. 闪点(ºC):未确定 9. 比旋光度(º):未确定 10. 自燃点或引燃温度(ºC):未确定 11. 蒸气压(20ºC):未确定 12. 饱和蒸气压(kPa,60ºC):未确定 13. 燃烧热(KJ/mol):未确定 14. 临界温度(ºC):未确定 15. 临界压力(KPa):未确定 16. 油水(辛醇/水)分配系数的对数值:未确定 17. 爆炸上限(%,V/V):未确定 18. 爆炸下限(%,V/V):未确定 19. 溶解性:未确定 |
Synonym:N-(p-Tolyl)piperazine dihydrochlorid Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: 36/37/38 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin.Hygroscopic (absorbs moisture from the air). Potential Health Effects Eye: Causes eye irritation. Skin: Causes skin irritation. May be harmful if absorbed through the skin. Ingestion: May cause irritation of the digestive tract. May be harmful if swallowed. Inhalation: Causes respiratory tract irritation. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Avoid generating dusty conditions. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 13078-14-3: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: Not available. Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 214 - 216 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C11H16N2.2HCl Molecular Weight: 249.18 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Incompatible materials, exposure to moist air or water. Incompatibilities with Other Materials: Strong oxidizing agents. Hazardous Decomposition Products: Hydrogen chloride, carbon monoxide, oxides of nitrogen, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 13078-14-3 unlisted. LD50/LC50: Not available. Carcinogenicity: 1-(4-Methylphenyl)piperazine dihydrochloride - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Shipping Name: Not regulated. Hazard Class: UN Number: Packing Group: IMO Shipping Name: Not regulated. Hazard Class: UN Number: Packing Group: RID/ADR Shipping Name: Not regulated. Hazard Class: UN Number: Packing group: Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XI Risk Phrases: R 36/37/38 Irritating to eyes, respiratory system and skin. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 Wear suitable gloves and eye/face protection. WGK (Water Danger/Protection) CAS# 13078-14-3: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 13078-14-3 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 13078-14-3 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A |
毒理学数据: 主要的刺激性影响: 在皮肤上面:刺激皮肤和粘膜 在眼睛上面:刺激的影响 致敏作用:没有已知的敏化现象 生态学数据: 通常对水体是稍微有害的,不要将未稀释或大量产品接触地下水,水道或污水系统,未经政府许可勿将材料排入周围环境。
|
危害码 (欧洲) | Xi:Irritant; |
---|---|
风险声明 (欧洲) | R36/37/38 |
安全声明 (欧洲) | S26-S37/39 |
~73% 13078-14-3 |
文献:Journal of Chemical Research, , vol. 35, # 1 p. 43 - 46 |