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间苯二甲酰氯

间苯二甲酰氯用途

【用途一】
用作农药、医药、高分子中间体
【用途二】
可用于合成芳纶、聚丙烯酸酯、耐高温树脂、染料、颜料、医药以及农药等
【用途三】
间苯二甲酰氯可用作芳香类纤维类的原料。

间苯二甲酰氯名称

[ CAS 号 ]:
99-63-8

[ 中文名 ]:
间苯二甲酰氯

[ 英文名 ]:
m-phthaloyl chloride

[中文别名 ]:

[英文别名 ]:

EINECS 202-774-7
Isophthaloyl dichloride
1,3-Benzenedicarbonyl dichloride
MFCD00000678
benzene-1,3-dicarbonyl dichloride
isophthalic acid dichloride
m-phthaloyl chloride

间苯二甲酰氯物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
276.7±13.0 °C at 760 mmHg

[ 熔点 ]:
43-44 °C(lit.)

[ 分子式 ]:
C₈H₄Cl₂O₂

[ 分子量 ]:
203.022

[ 闪点 ]:
131.9±15.4 °C

[ 精确质量 ]:
201.958832

[ PSA ]:
34.14000

[ LogP ]:
2.48

[ 外观性状 ]:
结晶固体

[ 蒸汽压 ]:
0.0±0.6 mmHg at 25°C

[ 折射率 ]:
1.571

[ 储存条件 ]:
库房通风低温干燥,与碱、氧化剂分开存放

[ 水溶解性 ]:
reacts

间苯二甲酰氯MSDS

间苯二甲酰氯毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NT2625000

CHEMICAL NAME :: Isophthaloyl chloride

CAS REGISTRY NUMBER :: 99-63-8

BEILSTEIN REFERENCE NO. :: 0638342

LAST UPDATED :: 199710

DATA ITEMS CITED :: 13

MOLECULAR FORMULA :: C8-H4-Cl2-O2

MOLECULAR WEIGHT :: 203.02

WISWESSER LINE NOTATION :: GVR CVG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Open irritation test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 11/3/1971

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 11/3/1971 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969 Volume(issue)/page/year: -,475,1969

TYPE OF TEST :: LC - Lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >31 gm/m3/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533736

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2221 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal) Behavioral - changes in motor activity (specific assay)

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 47(7),75,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1175 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal) Behavioral - changes in motor activity (specific assay)

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 47(7),75,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1410 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 28,313,1974 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1817 mg/kg/22W-I

TOXIC EFFECTS :: Blood - changes in leukocyte (WBC) count Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 47(7),75,1982

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 10 gm/kg/2W-I

TOXIC EFFECTS :: Gastrointestinal - alteration in gastric secretion Related to Chronic Data - death

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533736 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4719 No. of Facilities: 23 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 45 (estimated)

间苯二甲酰氯安全信息

[ 符号 ]:

GHS05, GHS06

[ 信号词 ]:
Danger

[ 危害声明 ]:
H312-H314-H331

[ 警示性声明 ]:
P261-P280-P305 + P351 + P338-P310

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
C:Corrosive

[ 风险声明 (欧洲) ]:
R34

[ 安全声明 (欧洲) ]:
S26-S36/37/39-S45-S7/8-S24/25

[ 危险品运输编码 ]:
UN 3261 8/PG 2

[ WGK德国 ]:
1

[ RTECS号 ]:
NT2625000

[ 包装等级 ]:
II

[ 危险类别 ]:
8

[ 海关编码 ]:
29173940

间苯二甲酰氯合成路线

间苯二甲酰氯上下游产品

间苯二甲酰氯上游产品

间苯二甲酰氯下游产品

间苯二甲酰氯制备

有氯化亚砜法、五氯化磷法、光气法、间苯二甲酸二甲酯氯化法、间苯二甲酸氯化法。较多采用光气法，通常在甲酰胺系催化剂存在下进行光气化反应。如果先使间苯二甲酸转变成分子间酸酐，然后进行光气化反应，间苯二甲酰氯本身双作为反应溶剂使用，可以获得较高收率。

间苯二甲酰氯海关

[ 海关编码 ]: 2917399090

[ 中文概述 ]:
2917399090 其他芳香多元羧酸. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 对苯二甲酸请注明4-CBA值, 对苯二甲酸请注明P-TL酸值, 对苯二甲酸请注明色度, 对苯二甲酸请注明水分

[ Summary ]:
2917399090 aromatic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

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