核糖核酸酶T1 来源于米曲霉(色谱纯化)

核糖核酸酶T1 来源于米曲霉(色谱纯化)用途

核糖核酸酶T1(Rnase T1)通常用于生化研究。核糖核酸酶T1是一种能特异性降解单链RNA的核酸内切酶。核糖核酸酶T1可以形成核苷2',3'-环磷酸中间体,以切断3'-鸟苷残基和相邻核苷5'-OH基团之间的磷酸二酯酶键,产生3'-GMP末端寡核苷酸[1]。

核糖核酸酶T1 来源于米曲霉(色谱纯化)名称

[ CAS 号 ]:
9026-12-4

[ 中文名 ]:
核糖核酸酶 T1 (米曲酶)

[ 英文名 ]:
Ribonuclease T1 from Aspergillus oryzae(Chromatographically Purif.)

[英文别名 ]:

MFCD00132191

核糖核酸酶T1 来源于米曲霉(色谱纯化)生物活性

[ 描述 ]:

[ 相关类别 ]:

信号通路 >> 细胞周期/DNA损伤 >> DNA/RNA合成

研究领域 >> 其他

[参考文献]

[1]. Heinemann U, et al. Crystallographic study of mechanism of ribonuclease T1-catalysed specific RNA hydrolysis. J Biomol Struct Dyn. 1983 Oct;1(2):523-38.

核糖核酸酶T1 来源于米曲霉(色谱纯化)物理化学性质

[ 分子量 ]:
384.41

[ 外观性状 ]:
ammonium sulfate suspension

[ 储存条件 ]:
2-8°C

核糖核酸酶T1 来源于米曲霉(色谱纯化)安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
RF0753000

核糖核酸酶T1 来源于米曲霉(色谱纯化)文献

Template-directed ligation of tethered mononucleotides by t4 DNA ligase for kinase ribozyme selection.

PLoS ONE 5(8) , e12368, (2010)

In vitro selection of kinase ribozymes for small molecule metabolites, such as free nucleosides, will require partition systems that discriminate active from inactive RNA species. While nucleic acid c...

FMRP mediates mGluR5-dependent translation of amyloid precursor protein.

PLoS Biol. 5 , e52, (2007)

Amyloid precursor protein (APP) facilitates synapse formation in the developing brain, while beta-amyloid (Abeta) accumulation, which is associated with Alzheimer disease, results in synaptic loss and...

A biphasic pattern of gene expression during mouse retina development.

BMC Dev. Biol. 6 , 48, (2006)

Between embryonic day 12 and postnatal day 21, six major neuronal and one glia cell type are generated from multipotential progenitors in a characteristic sequence during mouse retina development. We ...

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