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辛基三嗪酮

辛基三嗪酮用途

Ethylhexyl triazone 是可用于商业防晒剂的紫外线-B (UV-B) 化学过滤剂。

辛基三嗪酮名称

[ CAS 号 ]:
88122-99-0

[ 中文名 ]:
辛基三嗪酮

[ 英文名 ]:
Ethylhexyl triazone

[中文别名 ]:

[英文别名 ]:

Uvinul T150
UVT-150
Octyl triazone
Ethylhexyl triazone
Uvinul T 150

辛基三嗪酮生物活性

[ 描述 ]:

Ethylhexyl triazone 是可用于商业防晒剂的紫外线-B (UV-B) 化学过滤剂。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 其他

[体外研究]

乙基己基三嗪(EHT)的一个性质是其大分子量(823.07g/mol);这种过滤器不太可能渗透皮肤,从而减少与这种皮肤渗透相关的效果。它在UV-B区域显示出广泛的吸收特征,对于乙基己基三嗪-二恶烷和乙基己基三嗪-甲醇,最大吸收分别为~311和~313 nm [1]。

[参考文献]

[1]. Pinto-Bazurco Mendieta MA, et al. Highly potent and selective nonsteroidal dual inhibitors of CYP17/CYP11B2 for the treatment ofprostate cancer to reduce risks of cardiovascular diseases. J Med Chem. 2013 Aug 8;56(15):6101-7.

[相关活性小分子]

辛基三嗪酮物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
869.5±75.0 °C at 760 mmHg

[ 熔点 ]:
128°

[ 分子式 ]:
C₄₈H₆₆N₆O₆

[ 分子量 ]:
823.074

[ 闪点 ]:
479.6±37.1 °C

[ 精确质量 ]:
822.504395

[ PSA ]:
153.66000

[ LogP ]:
15.53

[ 蒸汽压 ]:
0.0±3.3 mmHg at 25°C

[ 折射率 ]:
1.576

[ 储存条件 ]:
2-8°C

辛基三嗪酮安全信息

[ 危害声明 ]:
H413

[ 风险声明 (欧洲) ]:
53

[ 安全声明 (欧洲) ]:
61

[ 危险品运输编码 ]:
NONH for all modes of transport

辛基三嗪酮合成路线

详细合成路线

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辛基三嗪酮文献

In vitro evaluation of Sun Protection Factor and stability of commercial sunscreens using mass spectrometry.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 988 , 13-9, (2015)

Sunlight exposure causes several types of injury to humans, especially on the skin; among the most common harmful effects due to ultraviolet (UV) exposure are erythema, pigmentation and lesions in DNA...

Concentrations and specific loads of UV filters in sewage sludge originating from a monitoring network in Switzerland.

Chemosphere 62(6) , 915-25, (2006)

Many substances related to human activities end up in wastewater and accumulate in sewage sludge. The present study focuses on the analysis of widely used UV filters 3-(4-methylbenzylidene) camphor (4...

Quantification of sunscreen ethylhexyl triazone in topical skin-care products by normal-phase TLC/densitometry.

ScientificWorldJournal 2012 , 807516, (2012)

Ethylhexyl triazone (ET) was separated from other sunscreens such as avobenzone, octocrylene, octyl methoxycinnamate, and diethylamino hydroxybenzoyl hexyl benzoate and from parabens by normal-phase H...

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