<生产厂家价格>

米法莫肽

米法莫肽用途

Mifamurtide(CGP19835; MTP-PE)可作用于骨肉瘤。

米法莫肽名称

[ CAS 号 ]:
83461-56-7

[ 中文名 ]:
米伐木肽

[ 英文名 ]:
Mifamurtide

[中文别名 ]:

米法莫肽

[英文别名 ]:

Mifamurtide
muramyl tripeptide phosphatidylethanolamine

米法莫肽生物活性

[ 描述 ]:

Mifamurtide(CGP19835; MTP-PE)可作用于骨肉瘤。

[ 相关类别 ]:

信号通路 >> 跨膜转运 >> TRP频道

研究领域 >> 癌症

[参考文献]

[1]. Frampton, J.E., Mifamurtide: a review of its use in the treatment of osteosarcoma. Paediatr Drugs, 2010. 12(3): p. 141-53.

[2]. Mifamurtide: CGP 19835, CGP 19835A, L-MTP-PE, liposomal MTP-PE, MLV 19835A, MTP-PE, muramyltripeptide phosphatidylethanolamine. Drugs R D, 2008. 9(2): p. 131-5.

[相关活性小分子]

辣椒碱 | 辣椒平 | 5-(N-乙基-N-异丙基)阿米洛利 | 氯化二亚苯基碘鎓 | 2-(1,3-二甲基-2,6-二氧代-2,3-二氢-1H-嘌呤-7(6H)-基)-N-(4-异丙基苯基)乙酰胺 | 1-[2-(4-甲氧基)-2-[3-(4-甲氧基苯基)丙氧基]乙基]咪唑 | HC-067047 | AMG9810 | GSK1016790A | SAR7334 | PF-4840154 | RN-1734 | AMG 517 | 3-(4-氯苯基)-N-(3-甲氧基苯基)-2-丙烯酰胺 | 冰素

米法莫肽物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 分子式 ]:
C₅₉H₁₀₉N₆O₁₉P

[ 分子量 ]:
1237.499

[ 精确质量 ]:
1236.748535

[ PSA ]:
385.91000

[ LogP ]:
10.98

[ 折射率 ]:
1.530

[ 储存条件 ]:
2-8℃

米法莫肽安全信息

米法莫肽文献

Muramyl tripeptide (mifamurtide) for the treatment of osteosarcoma.

Expert Rev. Anticancer Ther. 9(8) , 1035-49, (2009)

Osteosarcoma is an ultraorphan disease. There are approximately 1000 new patients diagnosed with osteosarcoma each year in the USA and Europe. Current treatment for osteosarcoma utilizes multiagent ch...

Imunomodulative effect of liposomized muramyltripeptide phosphatidylethanolamine (L-MTP-PE) on mice with alveolar echinococcosis and treated with albendazole.

Parasitol. Res. 103(4) , 919-29, (2008)

The effect of liposomized muramyltripeptide phosphatidylethanolamine (L-MTP-PE) administered separately or with anthelmintic albendazole (ABZ) on cellular immunity of mice with alveolar echinococcosis...

In vitro and in vivo enhancement of canine pulmonary alveolar macrophage cytotoxic activity against canine osteosarcoma cells.

Cancer Biother. Radiopharm. 14(2) , 121-8, (1999)

The combination of chemotherapy with immunotherapy may offer an advantage over either therapy alone and provide a greater potential for total tumor eradication. Monocyte/macrophage-mediated tumor cell...

更多文献