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盐酸班布特罗

盐酸班布特罗用途

Bambuterol盐酸盐是肾上腺素受体长效激动剂,Terbutaline的前体药物。

盐酸班布特罗名称

[ CAS 号 ]:
81732-46-9

[ 中文名 ]:
盐酸班部特罗

[ 英文名 ]:
Bambuterol Hydrochloride

[中文别名 ]:

[英文别名 ]:

(±)-Bambuterol hydrochloride
Bambuterol hydrochloride
UNII:786Q84QZ3F
MFCD03427293
Bambec
Bambuterol (hydrochloride)

盐酸班布特罗生物活性

[ 描述 ]:

Bambuterol盐酸盐是肾上腺素受体长效激动剂,Terbutaline的前体药物。

[ 相关类别 ]:

信号通路 >> G 蛋白偶联受体/G 蛋白 >> 肾上腺素能受体

研究领域 >> 其他

[参考文献]

[1]. Bambuterol, From Wikipedia

[相关活性小分子]

盐酸班布特罗物理化学性质

[ 密度 ]:
1.154g/cm3

[ 沸点 ]:
500.9ºC at 760 mmHg

[ 熔点 ]:
222-224ºC

[ 分子式 ]:
C₁₈H₃₀ClN₃O₅

[ 分子量 ]:
403.901

[ 闪点 ]:
256.7ºC

[ 精确质量 ]:
403.187408

[ PSA ]:
91.34000

[ LogP ]:
3.42180

[ 外观性状 ]:
白色固体

[ 折射率 ]:
1.533

[ 储存条件 ]:
-20°C Freezer

[ 水溶解性 ]:
H2O: ~33 mg/mL, soluble

盐酸班布特罗MSDS

详细MSDS(安全技术说明书)

盐酸班布特罗安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

盐酸班布特罗文献

Chiral analysis of bambuterol, its intermediate and active drug in human plasma by liquid chromatography-tandem mass spectrometry: Application to a pharmacokinetic study.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 997 , 38-44, (2015)

A sensitive liquid chromatography-tandem mass spectrometry (LC-MS/MS) method has been developed for simultaneous chiral analysis of an antiasthma drug bambuterol, its key intermediate monocarbamate ba...

Simultaneous determination of bambuterol and its two major metabolites in human plasma by hydrophilic interaction ultra-performance liquid chromatography-tandem mass spectrometry.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 967 , 225-34, (2014)

In this study, a rapid and sensitive hydrophilic interaction ultra-performance liquid chromatography-tandem mass spectrometry (HILIC-UPLC-MS/MS) method was developed for simultaneous determination of ...

Pharmacokinetics of bambuterol during oral administration of plain tablets and solution to healthy adults.

Br. J. Clin. Pharmacol. 49 , 199-206, (2000)

The pharmacokinetics of orally administered bambuterol were investigated in healthy adult subjects, with particular regard to time to steady state, pharmacokinetic linearity, intraindividual variabili...

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