铬酸铅

铬酸铅用途

【用途一】
用于油漆、油墨、塑料、橡胶等行业
【用途二】
用作分析试剂和油漆的颜料
【用途三】
用作油性和合成树脂涂料的原料，用于印刷油墨、水彩、油彩、颜料。还用作色纸、橡胶和塑料制品的着色剂。
【用途四】
煤质和碳氢分析,微量分析试剂。用于制油漆、油墨、水彩、颜料, 还用于色纸、橡胶、塑料制品的着色。

铬酸铅名称

[ CAS 号 ]:
7758-97-6

[ 中文名 ]:
铬酸铅(II)

[ 英文名 ]:
Lead(2+) dioxido(dioxo)chromium

[中文别名 ]:

[英文别名 ]:

EINECS 231-846-0
Lead(2+) dioxido(dioxo)chromium
Lead(II) chromate
Lead chromate
MFCD00011158
Chromium, diolatodioxo-, lead(2+) salt (1:1)

铬酸铅物理化学性质

[ 密度 ]:
6,3 g/cm3

[ 熔点 ]:
844°C

[ 分子式 ]:
CrO₄Pb

[ 分子量 ]:
323.19400

[ 精确质量 ]:
323.89700

[ PSA ]:
80.26000

[ 外观性状 ]:
黄色或橙黄色粉末。

[ 储存条件 ]:
室温

[ 稳定性 ]:
Stable. Reacts violently with ferric ferrocyanide.

[ 水溶解性 ]:
Insoluble.

铬酸铅MSDS

详细MSDS(安全技术说明书)

铬酸铅毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GB2975000

CAS REGISTRY NUMBER :: 7758-97-6

LAST UPDATED :: 199712

DATA ITEMS CITED :: 54

MOLECULAR FORMULA :: Cr-O4.Pb

MOLECULAR WEIGHT :: 323.19

WISWESSER LINE NOTATION :: PB CR-O4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >12 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD75 - Lethal Dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 156 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 11250 mg/kg/90D-C

TOXIC EFFECTS :: Behavioral - ataxia Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 135 mg/kg

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Tumorigenic - tumors at site of application

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 324 mg/kg/39W-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Kidney, Ureter, Bladder - Kidney tumors Tumorigenic - tumors at site of application

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 135 mg/kg

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application

TYPE OF TEST :: Micronucleus test

MUTATION DATA

TYPE OF TEST :: Mutation in mammalian somatic cells

TEST SYSTEM :: Rodent - hamster Ovary

REFERENCE :: CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 13,2053,1992 *** REVIEWS *** ACGIH TLV-Suspected human carcinogen DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-TWA 0.05 mg/m3, as Pb DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-TWA 0.012 mg/m3, as Cr DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 IARC Cancer Review:Human Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 23,205,1980 IARC Cancer Review:Human Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 49,49,1990 IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 23,205,1980 IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 49,49,1990 IARC Cancer Review:Group 1 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 49,49,1990 *** U.S. STANDARDS AND REGULATIONS *** OSHA PEL (Gen Indu):CL 0.1 mg(CrO3)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):CL 0.1 mg(CrO3)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):CL 0.1 mg(CrO3)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):CL 0.1 mg(CrO3)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 0.05 mg/m3;Carcinogen JAN 1993 OEL-BELGIUM:TWA 0.05 mg/m3;Carcinogen JAN 1993 OEL-FINLAND;Carcinogen JAN 1993 OEL-GERMANY;Carcinogen JAN 1993 OEL-THE NETHERLANDS:TWA 0.05 mg/m3 JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO CHROMIUM(VI)-air:10H CA TWA 0.001 mg(Cr)/m3 REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO LEAD, INORGANIC-air:10H TWA <0.1 mg(Pb)/m3 REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81876 No. of Facilities: 12060 (estimated) No. of Industries: 173 No. of Occupations: 87 No. of Employees: 131959 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81876 No. of Facilities: 1628 (estimated) No. of Industries: 33 No. of Occupations: 28 No. of Employees: 31932 (estimated) No. of Female Employees: 8639 (estimated)

铬酸铅安全信息

[ 符号 ]:

GHS08, GHS09

[ 信号词 ]:
Danger

[ 危害声明 ]:
H350-H360Df-H373-H410

[ 警示性声明 ]:
P201-P260-P280-P308 + P313

[ 危害码 (欧洲) ]:
T:Toxic;N:Dangerousfortheenvironment;

[ 风险声明 (欧洲) ]:
R33;R40;R50/53;R61;R62

[ 安全声明 (欧洲) ]:
S53-S45-S60-S61

[ 危险品运输编码 ]:
UN 3077 9/PG 3

[ WGK德国 ]:
3

[ RTECS号 ]:
GB2975000

[ 包装等级 ]:
III

[ 危险类别 ]:
6.1

铬酸铅制备

1.硝酸铅法先将氧化铅加入带搅拌的反应器中，在搅拌下缓慢加入硝酸进行反应生成硝酸铅溶液，然后将硝酸铅溶液和重铬酸钠溶液进行反应生成铬酸铅，经过滤、干燥、粉碎，制得铬酸铅成品。其反应式如下：
PbO+2HNO3pb(NO3）2＋H2O
2Pb(NO3）2+Na2Cr2O7＋H2O2PbＣCrO4＋2NaNO3＋2HNO3 2.向醋酸铅溶液中滴加铬酸钠制得铬酸铅沉淀。过滤，用水洗涤，即得铬酸铅晶体。 3. 采用硝酸法。以青铅、硝酸和红矾钠为主要原料，首先将铅锭爆铅，用硝酸溶解制成硝酸铅溶液，然后在合成桶内加入红矾钠溶液和硝酸铅溶液进行合成，经水洗后进行表面处理，然后经水洗、烘干、粉碎、包装，即为成品。 4. 将纯的三水合醋酸铅溶解于热水，制成13%溶液，过滤（若溶液浑浊，则过滤前需加入少量醋酸）。然后加入事先过滤好的7%的重铬酸钠溶液，充分搅拌下进行反应：待反应液澄清后过滤，吸滤所得结晶并用水洗涤至洗液中杂质含量合格，滤干后于100～110℃下干燥，并研细即为成品。

铬酸铅文献

Comparison of two particulate hexavalent chromium compounds: Barium chromate is more genotoxic than lead chromate in human lung cells.

Environ. Mol. Mutagen. 44(2) , 156-62, (2004)

Particulate hexavalent chromium [Cr(VI)] compounds are well-established human lung carcinogens. However, their carcinogenic mechanisms are poorly understood as most investigators have used soluble Cr(...

Particulate and soluble hexavalent chromium are cytotoxic and genotoxic to human lung epithelial cells.

Mutat. Res. 610(1-2) , 2-7, (2006)

Particulate hexavalent chromium (Cr(VI)) is a well-established human lung carcinogen. It is currently a major public health concern, there is widespread exposure to it in occupational settings and to ...

Homologous recombination repair protects against particulate chromate-induced chromosome instability in Chinese hamster cells.

Mutat. Res. 625(1-2) , 145-54, (2007)

Particulate hexavalent chromium [Cr(VI)] compounds are well-established human carcinogens. Cr(VI)-induced tumors are characterized by chromosomal instability (CIN); however, the mechanisms of this eff...

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铬酸铅