7-二乙氨基-3-(4-马来酰亚胺苯基)-4-甲基香豆素

用途

CPM是一种马来酰亚胺衍生物,用作蓝色荧光硫醇活性染料。激发/发射最大值为384/470 nm[1]。

名称

[ CAS 号 ]:
76877-33-3

[ 中文名 ]:
7-二乙氨基-3-(4-马来酸亚胺苯基-4-甲基香豆素

[ 英文名 ]:
7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin

[中文别名 ]:

[英文别名 ]:

生物活性

[ 描述 ]:

CPM是一种马来酰亚胺衍生物,用作蓝色荧光硫醇活性染料。激发/发射最大值为384/470 nm[1]。

[ 相关类别 ]:

研究领域 >> 其他
信号通路 >> 其他 >> 其他

[参考文献]

[1]. Grossman SH. Resonance energy transfer between the active sites of myocardial-type creatine kinase (isozyme MB). Biochemistry. 1983 Nov 8;22(23):5369-75.

物理化学性质

[ 密度 ]:
1.302 g/cm3

[ 沸点 ]:
618.7ºC at 760 mmHg

[ 分子式 ]:
C24H22N2O4

[ 分子量 ]:
402.44200

[ 闪点 ]:
328ºC

[ 精确质量 ]:
402.15800

[ PSA ]:
70.83000

[ LogP ]:
4.10900

[ 外观性状 ]:
固体

[ 折射率 ]:
1.648

[ 储存条件 ]:
-20°C, 密封, 干燥

MSDS

安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

文献

Co-expression of human agouti-related protein enhances expression and stability of human melanocortin-4 receptor.

Biochem. Biophys. Res. Commun. 456(1) , 116-21, (2014)

G protein-coupled receptors (GPCRs) represent the largest family of transmembrane signaling proteins, and they are considered major targets of approximately half of all therapeutic agents. Human melan...

Identification of 2-[2-(4-tert-butylphenyl)ethyl]-N-(4-fluorophenyl)-1,2,3,4-tetrahydroisoquinoline-6-sulfonamide (29) as an orally available MGAT2 inhibitor.

Bioorg. Med. Chem. 23 , 5922-31, (2015)

MGAT2 (monoacylglycerol acyltransferase 2) is expected to be an attractive target for the drug treatment of obesity, diabetes, and other disease. We describe our exploration and structure-activity rel...

N-terminal region of the catalytic domain of human N-myristoyltransferase 1 acts as an inhibitory module.

PLoS ONE 10 , e0127661, (2015)

N-myristoyltransferase (NMT) plays critical roles in the modulation of various signaling molecules, however, the regulation of this enzyme in diverse cellular states remains poorly understood. We prov...


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热门化合物

CAS号[76877-33-3]化源网提供[7-二乙氨基-3-(4-马来酰亚胺苯基)-4-甲基香豆素]MSDS、说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。>>电脑版:7-二乙氨基-3-(4-马来酰亚胺苯基)-4-甲基香豆素

标题:76877-33-3_CAS号:76877-33-3_7-二乙氨基-3-(4-马来酰亚胺苯基)-4-甲基香豆素 - 化源网 地址:https://www.chemsrc.com/amp/cas/76877-33-3_673542.html