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11-((5-二甲基氨基萘-1-磺酰基) 氨基)十一酸

用途

DAUDA(11-(丹酰氨基)十一酸)是一种环境敏感的荧光脂肪酸类似物。DAUDA在进入结合蛋白时改变其强度和荧光发射光谱。DAUDA用于测定天然脂肪酸对曼氏血吸虫Sm14脂肪酸结合蛋白多晶型的相对亲和力【1】。

名称

[ CAS 号 ]:
73025-02-2

[ 中文名 ]:
11-((5-二甲基氨基萘-1-磺酰基) 氨基)十一酸

[ 英文名 ]:
DAUDA

[英文别名 ]:

11D
DAUDA
Dauda-11

生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 其他

[参考文献]

[1]. Ramos CR, et al. Gene structure and M20T polymorphism of the Schistosoma mansoni Sm14 fatty acid-binding protein. Molecular, functioanl, and immunoprotection analysis. J Biol Chem. 2003; 278(15):12745-51.

物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
607.9±53.0 °C at 760 mmHg

[ 分子式 ]:
C₂₃H₃₄N₂O₄S

[ 分子量 ]:
434.592

[ 闪点 ]:
321.5±30.9 °C

[ 精确质量 ]:
434.223938

[ PSA ]:
95.09000

[ LogP ]:
5.87

[ 蒸汽压 ]:
0.0±1.8 mmHg at 25°C

[ 折射率 ]:
1.573

[ 储存条件 ]:
-20°C，避光

MSDS

详细MSDS(安全技术说明书)

安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
36/37/38

[ 安全声明 (欧洲) ]:
26

[ 危险品运输编码 ]:
NONH for all modes of transport

[ 海关编码 ]:
2935009090

海关

[ 海关编码 ]: 2935009090

[ 中文概述 ]:
2935009090 其他磺（酰）胺. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:35.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

文献

Lipid-free antigen B subunits from echinococcus granulosus: oligomerization, ligand binding, and membrane interaction properties.

PLoS Negl. Trop. Dis. 9(3) , e0003552, (2015)

The hydatid disease parasite Echinococcus granulosus has a restricted lipid metabolism, and needs to harvest essential lipids from the host. Antigen B (EgAgB), an abundant lipoprotein of the larval st...

Mutations of recombinant rat liver fatty acid-binding protein at residues 102 and 122 alter its structural integrity and affinity for physiological ligands.

Biochem. J. 314 ( Pt 3) , 943-9, (1996)

Rat liver fatty acid-binding protein (FABP) is able to accommodate a wide range of non-polar anions in addition to long-chain fatty acids. This property means that the liver protein is functionally di...

Binding of recombinant rat liver fatty acid-binding protein to small anionic phospholipid vesicles results in ligand release: a model for interfacial binding and fatty acid targeting.

Biochemistry 38(51) , 16932-40, (1999)

A number of intracellular proteins bind to negatively charged phospholipid membranes, and this interfacial binding results in a conformational change that modulates the activity of the protein. Using ...

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