精甲霜灵

精甲霜灵用途

Metalaxyl-M ((R)-Metalaxyl) 是甲氧基的 R 型活性对映体。Metalaxyl-M 是一种广谱杀菌 (fungicide) 试剂,抑制真菌中蛋白质和核糖体 RNA 的合成。Metalaxyl 用于研究由卵菌科的病原体引起的植物病害。

精甲霜灵名称

[ CAS 号 ]:
70630-17-0

[ 中文名 ]:
R-甲霜灵

[ 英文名 ]:
Metalaxyl-M

[中文别名 ]:

[英文别名 ]:

Metalaxyl-M
Metalaxil
methyl N-(methoxyacetyl)-N-2,6-xylyl-D-alaninate
Methenoxam
(-)-Metalaxyl
R-metalaxyl
(-)-(R)-metalaxyl
MFCD03701742
Methyl N-(methoxyacetyl)-N-(2,6-xylyl)-D-alaninate
Subdue Maxx

精甲霜灵生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 感染

信号通路 >> 抗感染 >> 真菌

[ 靶点 ]

IC50: fungi[1]

[参考文献]

[1]. Yinjun Zhang, et al. Bio-preparation of (R)-DMPM using whole cells of Pseudochrobactrum asaccharolyticum WZZ003 and its application on kilogram-scale synthesis of fungicide (R)-metalaxyl. Biotechnol Prog

精甲霜灵物理化学性质

[ 密度 ]:
1.117 g/cm3

[ 沸点 ]:
394.3ºC at 760 mmHg

[ 熔点 ]:
38.7ºC

[ 分子式 ]:
C₁₅H₂₁NO₄

[ 分子量 ]:
279.33200

[ 闪点 ]:
192.3ºC

[ 精确质量 ]:
279.14700

[ PSA ]:
55.84000

[ LogP ]:
1.84430

[ 外观性状 ]:
淡黄色至淡棕色浓液体

[ 折射率 ]:
1.527

[ 储存条件 ]:
0-6°C

精甲霜灵安全信息

[ 符号 ]:

GHS05, GHS07

[ 信号词 ]:
Danger

[ 危害声明 ]:
H302-H318

[ 警示性声明 ]:
P280-P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xn

[ 风险声明 (欧洲) ]:
R22

[ 安全声明 (欧洲) ]:
26-39-46

[ 危险品运输编码 ]:
NONH for all modes of transport

精甲霜灵文献

The cytotoxic and genotoxic effects of metalaxy-M on earthworms (Eisenia fetida).

Environ. Toxicol. Chem. 33(10) , 2344-50, (2014)

As the main optical isomer of metalaxyl, metalaxyl-M has been widely used worldwide in recent years because of its notable effect on the prevention and control of crop diseases. Together with the toxi...

Degradation of metalaxyl and mefenoxam and effects on the microbiological properties of tropical and temperate soils.

Int. J. Environ. Res. Public Health 2 , 272-85, (2006)

The degradation of various formulations of the racemic mixture and the enantiomers (including mefenoxam) of metalaxyl in typical soils from Germany and Cameroon in controlled incubation experiments wa...

Comparative genomics reveals insight into virulence strategies of plant pathogenic oomycetes.

PLoS ONE 8 , e75072, (2013)

The kingdom Stramenopile includes diatoms, brown algae, and oomycetes. Plant pathogenic oomycetes, including Phytophthora, Pythium and downy mildew species, cause devastating diseases on a wide range ...

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