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甘氨酰甘氨酰酪氨酰-精氨酸

甘氨酰甘氨酰酪氨酰-精氨酸用途

Papain inhibitor (Glycylglycyl-L-tyrosyl-L-arginine) 作为 Papain 的竞争性抑制剂,在 pH 6.2 时的 Ki 值为 9 μM。

甘氨酰甘氨酰酪氨酰-精氨酸名称

[ CAS 号 ]:
70195-20-9

[ 中文名 ]:
甘氨酰甘氨酰酪氨酰-精氨酸

[ 英文名 ]:
H-Gly-Gly-Tyr-Arg-OH

[英文别名 ]:

GLYCINE-GLYCINE-TYROSINE-ARGININE
PAPAIN INHIBITOR
glycyl-glycyl-tyrosyl-arginine
H-Gly-Gly-Tyr-Arg-OH

甘氨酰甘氨酰酪氨酰-精氨酸生物活性

[ 描述 ]:

Papain inhibitor (Glycylglycyl-L-tyrosyl-L-arginine) 作为 Papain 的竞争性抑制剂,在 pH 6.2 时的 Ki 值为 9 μM。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 代谢酶/蛋白酶 >> 组织蛋白酶

[ 靶点 ]

Papain[1].

[参考文献]

[1]. Plumb K, et al. Interaction of a ferrocenoyl-modified peptide with papain: toward protein-sensitive electrochemical probes. Bioconjug Chem. 2003 May-Jun;14(3):601-6.

甘氨酰甘氨酰酪氨酰-精氨酸物理化学性质

[ 密度 ]:
1.49g/cm3

[ 分子式 ]:
C₁₉H₂₉N₇O₆

[ 分子量 ]:
451.48

[ 精确质量 ]:
451.21800

[ PSA ]:
232.75000

[ LogP ]:
0.39100

[ 外观性状 ]:
白色粉末

[ 折射率 ]:
1.652

[ 储存条件 ]:
-20°C，密闭，干燥

甘氨酰甘氨酰酪氨酰-精氨酸安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

甘氨酰甘氨酰酪氨酰-精氨酸文献

A novel method for the incorporation of glycoprotein-derived oligosaccharides into neoglycopeptides.

Bioconjug. Chem. 3(5) , 391-6, (1992)

We describe a new method for the transfer of carbohydrate moieties to polypeptides in which complex carbohydrate, in the form of glycosyl amino acid, is removed from an available glycoprotein, derivat...

High-resolution separation of peptides by sodium dodecyl sulfate-polyacrylamide gel "focusing".

Electrophoresis 29 , 1749-52, (2008)

As a follow-up of our previous report (Anal. Chem. 2007, 79, 821-827) on analytical SDS-PAGE focusing, a refinement of the method for separation of peptides in the small to medium M(r) range (0.5-10 k...

Affinity chromatographic purification of papain.

Int. J. Pept. Protein Res. 13 , 296, (1979)

The reinvestigation of the affinity chromatographic method of purifying papain has been carried out. It has been reported that papain could be purified by taking advantage of the affinity of the enzym...

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