5-乙基-5-苯基咪唑烷-2,4-二酮
5-乙基-5-苯基咪唑烷-2,4-二酮名称
[ CAS 号 ]:
631-07-2
[ 中文名 ]:
5-乙基-5-苯基海因
[ 英文名 ]:
2,4-Imidazolidinedione,5-ethyl-5-phenyl-
[英文别名 ]:
- EINECS 211-150-3
- (+/-)-5-ethyl-5-phenylhydantoin
- MFCD00022401
5-乙基-5-苯基咪唑烷-2,4-二酮物理化学性质
[ 密度 ]:
1.173 g/cm3
[ 熔点 ]:
195-200ºC
[ 分子式 ]:
C11H12N2O2
[ 分子量 ]:
204.22500
[ 精确质量 ]:
204.09000
[ PSA ]:
58.20000
[ LogP ]:
1.78890
[ 外观性状 ]:
灰白色固体
[ 折射率 ]:
1.538
[ 储存条件 ]:
2-8°C
5-乙基-5-苯基咪唑烷-2,4-二酮MSDS
5-乙基-5-苯基咪唑烷-2,4-二酮毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MU2452000
- CHEMICAL NAME :
- Hydantoin, 5-ethyl-5-phenyl-
- CAS REGISTRY NUMBER :
- 631-07-2
- LAST UPDATED :
- 199012
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C11-H12-N2-O2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- LDTU** "Narkoseversuche mit Hoheren Alkoholen und Stickstoffderivaten, Dissertation," Leube, F., Pharmakologischen Institut der Universitat Tubingen, Fed. Rep. Ger., 1931 Volume(issue)/page/year: -,-,1931
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - excitement
- REFERENCE :
- HDTU** "Pharmakologische Prufung von Analgetika, Dissertation," Herrlen, G., Pharmakologischen Institut der Universitat Tubingen, Fed. Rep. Ger., 1933 Volume(issue)/page/year: -,-,1933
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig, Ger. Dem. Rep.) Volume(issue)/page/year: 4,1289,1935
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Amphibian - frog
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig, Ger. Dem. Rep.) Volume(issue)/page/year: 4,1289,1935
5-乙基-5-苯基咪唑烷-2,4-二酮安全信息
[ 符号 ]:
GHS07
[ 信号词 ]:
Warning
[ 危害声明 ]:
H302-H315-H319-H335
[ 警示性声明 ]:
P261-P305 + P351 + P338
[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves
[ 危害码 (欧洲) ]:
Xn: Harmful;
[ 风险声明 (欧洲) ]:
R22
[ 安全声明 (欧洲) ]:
26
[ 危险品运输编码 ]:
NONH for all modes of transport
[ WGK德国 ]:
2
[ RTECS号 ]:
MU2452000
5-乙基-5-苯基咪唑烷-2,4-二酮合成路线
5-乙基-5-苯基咪唑烷-2,4-二酮上下游产品
5-乙基-5-苯基咪唑烷-2,4-二酮上游产品
5-乙基-5-苯基咪唑烷-2,4-二酮下游产品
5-乙基-5-苯基咪唑烷-2,4-二酮文献
Chem. Res. Toxicol. 6(2) , 188-96, (1993)
The pharmacodynamics of rat hepatic cytochrome P450 2B (P450 2B) induction by phenobarbital (PB) and two structural congeners, dl-5-ethyl-5-phenylhydantoin (EPH) and dl-5-ethyl-5-phenyloxazolidinedion...
A markedly diminished pleiotropic response to phenobarbital and structurally-related xenobiotics in Zucker rats in comparison with F344/NCr or DA rats.Biochem. Pharmacol. 43(5) , 1079-87, (1992)
Phenobarbital (PB) and certain structurally-related compounds induce a variety of hepatic drug-metabolizing enzymes in many strains of rats. Thus, following administration of PB (300, 500 ppm), barbit...
Active-site characteristics of CYP2C19 and CYP2C9 probed with hydantoin and barbiturate inhibitors.Arch. Biochem. Biophys. 429(1) , 1-15, (2004)
Three series of N-3 alkyl substituted phenytoin, nirvanol, and barbiturate derivatives were synthesized and their inhibitor potencies were tested against recombinant CYP2C19 and CYP2C9 to probe the in...
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[5-乙基-5-苯基咪唑烷-2,4-二酮]化源网提供5-乙基-5-苯基咪唑烷-2,4-二酮CAS号631-07-2,5-乙基-5-苯基咪唑烷-2,4-二酮MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询5-乙基-5-苯基咪唑烷-2,4-二酮上化源网,专业又轻松。>>电脑版:5-乙基-5-苯基咪唑烷-2,4-二酮
标题:631-07-2_5-乙基-5-苯基咪唑烷-2,4-二酮CAS号:631-07-2_5-乙基-5-苯基咪唑烷-2,4-二酮【结构式 性质 英文】 - 化源网 地址:https://www.chemsrc.com/amp/cas/631-07-2_79246.html