<生产厂家价格>

1-(二氯乙酰基)-6-(2-呋喃甲酰氧基)-1,2,3,4-四氢喹啉

用途

Quinfamide 是一种抗阿米巴菌剂。Quinfamide可用于治疗阿米巴病、蠕虫病等热带寄生虫感染的疾病。

名称

[ CAS 号 ]:
62265-68-3

[ 中文名 ]:
喹法米特

[ 英文名 ]:
Quinfamide

[中文别名 ]:

呋醋喹酯

[英文别名 ]:

Quinfamido [INN-Spanish]
Quinfamide
Quinfamidum [INN-Latin]
EINECS 263-478-1
Amenide

生物活性

[ 描述 ]:

Quinfamide 是一种抗阿米巴菌剂。Quinfamide可用于治疗阿米巴病、蠕虫病等热带寄生虫感染的疾病。

[ 相关类别 ]:

信号通路 >> 抗感染 >> 寄生物

研究领域 >> 感染

[参考文献]

[1]. Davila-Gutierrez CE, et al. Nitazoxanide compared with quinfamide and mebendazole in the treatment of helminthic infections and intestinal protozoa in children. Am J Trop Med Hyg. 2002 Mar;66(3):251-4.

物理化学性质

[ 密度 ]:
1.428g/cm3

[ 沸点 ]:
551.3ºC at 760mmHg

[ 熔点 ]:
145-146ºC

[ 分子式 ]:
C₁₆H₁₃Cl₂NO₄

[ 分子量 ]:
354.18

[ 闪点 ]:
287.2ºC

[ 精确质量 ]:
353.02200

[ PSA ]:
59.75000

[ LogP ]:
3.64670

[ 折射率 ]:
1.599

[ 储存条件 ]:
2-8°C

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LU0215000

CHEMICAL NAME :: 2-Furancarboxylic acid, 1-(dichloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl ester

CAS REGISTRY NUMBER :: 62265-68-3

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C16-H13-Cl2-N-O4

MOLECULAR WEIGHT :: 354.20

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 22,599,1979

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - hamster

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 22,599,1979

安全信息

[ 海关编码 ]:
2934999090

合成路线

详细合成路线

海关

[ 海关编码 ]: 2934999090

[ 中文概述 ]:
2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%