钙离子载体

钙离子载体用途

Calcium ionophore I (ETH 1001) 是一种用于生物膜的选择性 Ca2+ 载体 (Ca2+ ionophore)。Calcium ionophore I 可用于Ca2+ 选择性微电极,可用于定量测定细胞内静息 Ca2+ 活性和缓慢变化的 Ca2+ 水平。

钙离子载体名称

[ CAS 号 ]:
58801-34-6

[ 中文名 ]:
钙离子载体I

[ 英文名 ]:
CA 1001

[中文别名 ]:

钙离子载体

[英文别名 ]:

EINECS 261-449-8
MFCD00042943

钙离子载体生物活性

[ 描述 ]:

[ 相关类别 ]:

信号通路 >> 跨膜转运 >> 钙通道

研究领域 >> 其他

[参考文献]

[1]. T R Hinds, et al. The effect of ETH 1001 on ion fluxes across red blood cell membranes. Cell Calcium. 1985 Jun;6(3):265-79.

[2]. D Ammann. Ca2+-selective microelectrodes. Cell Calcium. 1985 Apr;6(1-2):39-55.

钙离子载体物理化学性质

[ 密度 ]:
1g/cm3

[ 沸点 ]:
715.1ºC at 760mmHg

[ 分子式 ]:
C₃₈H₇₂N₂O₈

[ 分子量 ]:
684.98700

[ 闪点 ]:
386.3ºC

[ 精确质量 ]:
684.52900

[ PSA ]:
111.68000

[ LogP ]:
7.64160

[ 储存条件 ]:
2-8°C

钙离子载体MSDS

详细MSDS(安全技术说明书)

钙离子载体安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

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钙离子载体文献

Design, properties, and applications of neutral ionophores.

Meth. Enzymol. 56 , 439, (1979)

T-lineage cells require the thymus but not VDJ recombination to produce IL-17A and regulate granulopoiesis in vivo.

J. Immunol. 183 , 5685-93, (2010)

IL-17A and IL-17F regulate granulopoiesis and are produced by memory T cells. Rag1(-/-) recombinase-activating gene-deficient mice cannot produce mature T cells but maintain normal neutrophil counts. ...

Ca2+ transport mediated by a synthetic neutral Ca2+ -ionophore in biological membranes.

Biochim. Biophys. Acta 470 , 437, (1977)

The effect of a synthetic neutral ligand on the Ca2+ permeability of several biological membranes has been investigated. The ligand had been previously shown to possess Ca2+ -ionophoric activities in ...

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