地那林
地那林名称
[ CAS 号 ]:
58338-59-3
[ 中文名 ]:
地那林
[ 英文名 ]:
Benzamide,4-amino-N-(2-aminophenyl)-
[英文别名 ]:
- Goe-1734
- 4-Amino-N-(2'-aminophenyl)-benzamide
- Dinaline [INN]
- Dinalina [Spanish]
- 2',4-Diaminobenzanilide
- Dinaline [French]
- 2',4-Diaminobenzanilid
- Dinaline
- Dianiline
- Dinalinum [Latin]
地那林物理化学性质
[ 密度 ]:
1.314g/cm3
[ 沸点 ]:
367.2ºC at 760mmHg
[ 分子式 ]:
C13H13N3O
[ 分子量 ]:
227.26200
[ 闪点 ]:
175.9ºC
[ 精确质量 ]:
227.10600
[ PSA ]:
81.14000
[ LogP ]:
3.33870
[ 折射率 ]:
1.734
地那林毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CU8994000
- CHEMICAL NAME :
- Benzamide, 4-amino-N-(2-aminophenyl)-
- CAS REGISTRY NUMBER :
- 58338-59-3
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C13-H13-N3-O
- MOLECULAR WEIGHT :
- 227.29
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 95 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 625 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 630 mg/kg/6W-I
- TOXIC EFFECTS :
- Blood - changes in bone marrow (not otherwise specified) Blood - changes in erythrocyte (RBC) count Related to Chronic Data - death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 462 mg/kg/14W-I
- TOXIC EFFECTS :
- Blood - changes in bone marrow (not otherwise specified)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 6678 mg/kg/2Y-C
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Endocrine - adrenal cortex tumors Reproductive - Maternal Effects - uterus, cervix, vagina
MUTATION DATA
- TEST SYSTEM :
- Rodent - rat
- DOSE/DURATION :
- 10 mg/kg
- REFERENCE :
- CTRRDO Cancer Treatment Reports. (Washington, DC) V.60-71, 1976-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 69,1415,1985
地那林上下游产品
地那林上游产品
地那林下游产品
推荐生产厂家/供应商：
公司名：上海阿拉丁生化科技股份有限公司
区域：上海市浦东新区
价格：
￥2220.0/50mg
￥需询单/1g
￥需询单/1g
￥需询单/1g
联系人：阿拉丁李高志
产品详情：地那林
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相关化合物
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