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N,N-双(2-氯乙基)苯胺

N,N-双(2-氯乙基)苯胺名称

[ CAS 号 ]:
553-27-5

[ 中文名 ]:
N,N-双(2-氯乙基)苯胺

[ 英文名 ]:
N,N-bis-(2-Chloroethyl)aniline

[英文别名 ]:

Lymphoquine
Aniline mustard
Mesylerythrol
Lymphocin
Lymphochin
Lymphoquin
Lymphchin

N,N-双(2-氯乙基)苯胺物理化学性质

[ 密度 ]:
1.19 g/cm3

[ 沸点 ]:
304.1ºC at 760 mmHg

[ 分子式 ]:
C₁₀H₁₃Cl₂N

[ 分子量 ]:
218.12300

[ 闪点 ]:
137.7ºC

[ 精确质量 ]:
217.04300

[ PSA ]:
3.24000

[ LogP ]:
2.97060

[ 折射率 ]:
1.563

[ 储存条件 ]:
库房通风低温干燥,与食品原料分开存放

N,N-双(2-氯乙基)苯胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BW8225000

CHEMICAL NAME :: Aniline, N,N-bis(2-chloroethyl)-

CAS REGISTRY NUMBER :: 553-27-5

BEILSTEIN REFERENCE NO. :: 0880463

LAST UPDATED :: 199612

DATA ITEMS CITED :: 11

MOLECULAR FORMULA :: C10-H13-Cl2-N

MOLECULAR WEIGHT :: 218.14

WISWESSER LINE NOTATION :: G2NR&2G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 239 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 80 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 123 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 mg/m3/10M

TOXIC EFFECTS :: Behavioral - irritability Lungs, Thorax, or Respiration - acute pulmonary edema

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 52 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 125 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 375 mg/kg/35D-I

TOXIC EFFECTS :: Behavioral - food intake (animal) Liver - hepatitis, fibrous (cirrhosis, post-necrotic scarring) Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Primate - monkey

DOSE/DURATION :: 375 mg/kg/15D-I

TOXIC EFFECTS :: Gastrointestinal - other changes Blood - changes in bone marrow (not otherwise specified) Related to Chronic Data - death

MUTATION DATA

TYPE OF TEST :: DNA damage

TEST SYSTEM :: Rodent - mouse Lymphocyte

DOSE/DURATION :: 30 umol/L

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 44,78,1984

N,N-双(2-氯乙基)苯胺安全信息

[ 危害码 (欧洲) ]:
C

[ 海关编码 ]:
2921420090

N,N-双(2-氯乙基)苯胺合成路线

详细合成路线

N,N-双(2-氯乙基)苯胺海关

[ 海关编码 ]: 2921420090

[ 中文概述 ]:
2921420090 其他苯胺衍生物及其盐. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%