叶枯炔

叶枯炔用途

Cellocidin is a potent growth inhibitor for gammaherpesvirus-associated B-lymphomas that acts through activation of both the NF-κB and c-Myc-mediated signaling pathways.

叶枯炔名称

[ CAS 号 ]:
543-21-5

[ 中文名 ]:
叶枯炔

[ 英文名 ]:
NSC-65381

[中文别名 ]:

[英文别名 ]:

Cellocidin
2-butynediamide
Lenamycin
Acetylene dicarboxamide
acetylene dicarboxylic diamide
but-2-ynediamide
Renamycin
acetylene dicarboxylic acid diamide
acetylenedicarboxamide
EINECS 200-816-9

叶枯炔物理化学性质

[ 密度 ]:
1.41g/cm3

[ 沸点 ]:
294ºC at 760 mmHg

[ 熔点 ]:
179ºC

[ 分子式 ]:
C₄H₄N₂O₂

[ 分子量 ]:
112.08700

[ 闪点 ]:
131.6ºC

[ 精确质量 ]:
112.02700

[ PSA ]:
86.18000

[ 外观性状 ]:
Fine Crystalline Powder | Cream to beige

[ 蒸汽压 ]:
0.00167mmHg at 25°C

[ 折射率 ]:
1.56

[ 储存条件 ]:
库房通风低温干燥,与食品原料分开储运

叶枯炔MSDS

详细MSDS(安全技术说明书)

叶枯炔毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AO9900000

CHEMICAL NAME :: Acetylenedicarboxamide

CAS REGISTRY NUMBER :: 543-21-5

BEILSTEIN REFERENCE NO. :: 1756134

LAST UPDATED :: 199701

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C4-H4-N2-O2

MOLECULAR WEIGHT :: 112.10

WISWESSER LINE NOTATION :: ZV1UU1VZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 89200 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPIFAN Japan Pesticide Information. (Japan Plant Protection Assoc., 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) No.1-61, 1969-92. For publisher information, see AGJAEP. Volume(issue)/page/year: (1),15,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 667 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPIFAN Japan Pesticide Information. (Japan Plant Protection Assoc., 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) No.1-61, 1969-92. For publisher information, see AGJAEP. Volume(issue)/page/year: (1),15,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 11 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JAJAAA Journal of Antibiotics, Series A. (Tokyo, Japan) V.6-20, 1953-67. For publisher information, see JANTAJ. Volume(issue)/page/year: 11,81,1958

叶枯炔安全信息

[ 危害码 (欧洲) ]:
T

[ 风险声明 (欧洲) ]:
25-21

[ 安全声明 (欧洲) ]:
45-36/37-28A

[ 海关编码 ]:
2924199090

叶枯炔合成路线

详细合成路线

叶枯炔上下游产品

叶枯炔上游产品

叶枯炔下游产品

叶枯炔海关

[ 海关编码 ]: 2924199090

[ 中文概述 ]:
2924199090. 其他无环酰胺（包括无环氨基甲酸酯)(包括其衍生物及盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 包装

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

叶枯炔