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3,3'-二乙基硫二碳碘化氰

3,3'-二乙基硫二碳碘化氰用途

碘化二硫氮嗪是一种有效的广谱驱虫药。碘化二硫氮嗪可用于研究鞭虫病、圆线虫病、蛲虫病、蛔虫病和钩虫感染。碘化二硫氮嗪也是一种菁染料[1][2]。

3,3'-二乙基硫二碳碘化氰名称

[ CAS 号 ]:
514-73-8

[ 中文名 ]:
碘化噻唑青胺

[ 英文名 ]:
3,3'-Diethylthiadicarbocyanine iodide

[中文别名 ]:

[英文别名 ]:

3,3'-diethyl-2,2'-thiadicarbocyanine iodide
PARTEL
MFCD00074829
DELVEX
TELMID
ANELMID
3,3′-Diethylthiadicarbocyanine iodide
DTDC
EINECS 208-186-7
NETOCYD

3,3'-二乙基硫二碳碘化氰生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 感染

[参考文献]

[1]. SWARTZWELDER JC, et al. Dithiazanine, an effective broad-spectrum anthelmintic; results of therapy of trichuriasis, strongyloidiasis, enterobiasis, ascariasis, and hookworm infection. J Am Med Assoc. 1957 Dec 21;165(16):2063-7.

[2]. ABADIE SH, et al. A FATALITY ASSOCIATED WITH DITHIAZANINE IODIDE THERAPY. JAMA. 1965 Apr 26;192:326-7.

3,3'-二乙基硫二碳碘化氰物理化学性质

[ 熔点 ]:
249ºC

[ 分子式 ]:
C₂₃H₂₃IN₂S₂

[ 分子量 ]:
518.47700

[ 精确质量 ]:
518.03500

[ PSA ]:
65.29000

[ LogP ]:
2.58000

[ 外观性状 ]:
Powder | Green

[ 折射率 ]:
1.491

[ 储存条件 ]:
Poison room

[ 水溶解性 ]:
Soluble in methanol

3,3'-二乙基硫二碳碘化氰MSDS

3,3'-二乙基硫二碳碘化氰毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DL7060000

CHEMICAL NAME :: Benzothiazolium, 3-ethyl-2-(5-(3-ethyl-2-benzothiazolinylidene)-1,3-pe ntadienyl)-, iodide

CAS REGISTRY NUMBER :: 514-73-8

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C23-H23-N2-S2.I

MOLECULAR WEIGHT :: 518.50

WISWESSER LINE NOTATION :: T56 BNYSJ B2 CU2U2U1- CT56 BK DSJ B2 &I

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 10,897,1967

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#02015

3,3'-二乙基硫二碳碘化氰安全信息

[ 符号 ]:

GHS06

[ 信号词 ]:
Danger

[ 危害声明 ]:
H300-H315-H319-H335

[ 警示性声明 ]:
P261-P264-P301 + P310-P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
T+

[ 风险声明 (欧洲) ]:
R28;R36/37/38

[ 安全声明 (欧洲) ]:
S26-S28-S36/37-S45

[ 危险品运输编码 ]:
UN 2811

[ WGK德国 ]:
3

[ RTECS号 ]:
DL7060000

[ 包装等级 ]:
II

[ 危险类别 ]:
6.1

3,3'-二乙基硫二碳碘化氰合成路线

3,3'-二乙基硫二碳碘化氰文献

Structure-activity relationship of cyanine tau aggregation inhibitors.

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A structure-activity relationship for symmetrical cyanine inhibitors of human tau aggregation was elaborated using a filter trap assay. Antagonist activity depended on cyanine heterocycle, polymethine...

Three-dimensional fluorescence lifetime tomography.

Med. Phys. 32(4) , 992-1000, (2005)

Near-infrared fluorescence tomography using molecularly targeted lifetime-sensitive, fluorescent contrast agents have applications for early-stage cancer diagnostics. Yet, although the measurement of ...

Genetic screening using the colour change of a PNA-DNA hybrid-binding cyanine dye.

Nucleic Acids Res. 30(2) , E3, (2002)

As the relationship between human genes and various malfunctions and diseases becomes revealed at an ever-increasing pace, the need arises for the development of rapid genetic screening methods for di...

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