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3-哌啶甲酸乙酯

3-哌啶甲酸乙酯名称

[ CAS 号 ]:
5006-62-2

[ 中文名 ]:
3-哌啶甲酸乙酯

[ 英文名 ]:
Ethyl nipecotate

[中文别名 ]:

[英文别名 ]:

3-Piperidinecarboxylic acid, ethyl ester, (±)-
Ethyl nipecotate
Ethyl 3-piperidinecarboxylate
Nipecotinic acid ethyl ester
ethyl piperidine-3-carboxylate
Ethylpiperidin-3-carboxylat
3-Piperidinecarboxylic acid ethyl ester
EINECS 225-681-3
3-Piperidinecarboxylic acid, ethyl ester
MFCD00005991

3-哌啶甲酸乙酯物理化学性质

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
238.6±0.0 °C at 760 mmHg

[ 分子式 ]:
C₈H₁₅NO₂

[ 分子量 ]:
157.210

[ 闪点 ]:
90.6±0.0 °C

[ 精确质量 ]:
157.110275

[ PSA ]:
38.33000

[ LogP ]:
0.96

[ 外观性状 ]:
透明无色至黄色-棕色液体

[ 蒸汽压 ]:
0.0±0.4 mmHg at 25°C

[ 折射率 ]:
1.449

[ 储存条件 ]:
存放于惰性气体之中;避免空气

[ 水溶解性 ]:
miscible

3-哌啶甲酸乙酯MSDS

详细MSDS(安全技术说明书)

3-哌啶甲酸乙酯安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xi,C

[ 风险声明 (欧洲) ]:
R34

[ 安全声明 (欧洲) ]:
S26-S36/37/39-S45

[ WGK德国 ]:
3

[ 海关编码 ]:
2933399090

3-哌啶甲酸乙酯海关

[ 海关编码 ]: 2933399090

[ 中文概述 ]:
2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

3-哌啶甲酸乙酯文献

Synthesis of stereoisomers of antithrombotic nipecotamides.

Chirality 7 , 90, (1995)

The stereoisomers of alpha,alpha'-bis[3-(N,N-diethylcarbamoyl)-piperidino]-p-xylene (1) were synthesized. Rac ethyl nipecotate was resolved by diastereomeric (-)-D- and (+)-L-tartrate salt formation. ...

THIP analgesia: cross tolerance with morphine.

Life Sci. 32(19) , 2265-72, (1983)

THIP (4,5,6,7-tetrahydroisoxazolo (5,4-c) pyridone-3-ol), a direct acting GABA receptor agonist, has been shown to have antinociceptive properties. To determine whether tolerance develops to the analg...

(R)-nipecotic acid ethyl ester: a direct-acting cholinergic agonist that displays greater efficacy at M2 than at M1 muscarinic receptors.

J. Pharmacol. Exp. Ther. 242(1) , 173-8, (1987)

Previous reports have suggested that the ethyl ester of (R)-nipecotic acid ethyl ester [(R)-NAEE] displays cholinomimetic properties in vivo. The present study was undertaken to characterize more full...

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