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Alpha-胸苷

Alpha-胸苷名称

[ CAS 号 ]:
4449-43-8

[ 中文名 ]:
Alpha-胸苷

[ 英文名 ]:
ALPHA-THYMIDINE

[中文别名 ]:

α-胸苷

[英文别名 ]:

L-Dt
MFCD00069766
L-2'-deoxythymidine
Epavudine
2'-DEOXY-L-THYMIDINE
NV 02B
L-Deoxythymidine

Alpha-胸苷物理化学性质

[ 密度 ]:
1.452g/cm3

[ 分子式 ]:
C₁₀H₁₄N₂O₅

[ 分子量 ]:
242.22900

[ 精确质量 ]:
242.09000

[ PSA ]:
104.55000

[ 折射率 ]:
1.584

Alpha-胸苷MSDS

详细MSDS(安全技术说明书)

Alpha-胸苷安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

Alpha-胸苷文献

Synthesis and inhibitory activity of thymidine analogues targeting Mycobacterium tuberculosis thymidine monophosphate kinase

Bioorg. Med. Chem. 19(24) , 7603-1, (2011)

We report on Mycobacterium tuberculosis thymidine monophosphate kinase (TMPKmt) inhibitory activities of a series of new 3'- and 5'-modified thymidine analogues including α- and β-derivatives. In addi...

Rational design and 3D-pharmacophore mapping of 5'-thiourea-substituted alpha-thymidine analogues as mycobacterial TMPK inhibitors.

J. Chem. Inf. Model. 49 , 1070-1078, (2009)

Thymidine monophosphate kinase (TMPK) has emerged as an attractive target for developing inhibitors of Mycobacterium tuberculosis growth. In this study the receptor-independent (RI) 4D-QSAR formalism ...

Chemical synthesis of hydroxymethylphosphonate alpha-DNA.

Nucleic Acids Symp. Ser. 44 , 31-32, (2000)

In this paper, we report the synthesis of hydroxymethylphosphonate alpha-DNAs and related compounds by use of the H-phosphonate method. These modified alpha-DNAs were designed to improve the inherent ...

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