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2,3-二巯基丙磺酸钠

2,3-二巯基丙磺酸钠用途

橡胶和制药工业。重金属中毒解毒剂。

2,3-二巯基丙磺酸钠名称

[ CAS 号 ]:
4076-02-2

[ 中文名 ]:
2,3-二巯基丙磺酸钠

[ 英文名 ]:
unithiol

[中文别名 ]:

[英文别名 ]:

2,3-Dimercaptopropylsulphonica
Dimaval
DIMERCAPTOPROPANESULPHONICACID
unitiol
Sodium 2,3-disulfanyl-1-propanesulfonate
2,3-DICHLORO-5-FORMYLPYRIDINE
2,3-dimercaptopropane-1-sulfonic acid sodium salt
EINECS 223-796-3
MFCD00007523
sodium 2,3-disulfanylpropane-1-sulfonate

2,3-二巯基丙磺酸钠物理化学性质

[ 熔点 ]:
215 °C (dec.)

[ 分子式 ]:
C₃H₇NaO₃S₃

[ 分子量 ]:
210.271

[ 精确质量 ]:
209.945496

[ PSA ]:
143.18000

[ LogP ]:
0.84060

[ 外观性状 ]:
白色粉末

[ 储存条件 ]:
2-8°C

[ 水溶解性 ]:
H2O: 0.1 g/mL, clear

2,3-二巯基丙磺酸钠MSDS

详细MSDS(安全技术说明书)

2,3-二巯基丙磺酸钠毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TZ6420000

CHEMICAL NAME :: 1-Propanesulfonic acid, 2,3-dimercapto-, monosodium salt

CAS REGISTRY NUMBER :: 4076-02-2

LAST UPDATED :: 199309

DATA ITEMS CITED :: 12

MOLECULAR FORMULA :: C3-H7-O3-S3.Na

MOLECULAR WEIGHT :: 210.27

WISWESSER LINE NOTATION :: WSO&1YSH1SH &-NA-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1055 mg/kg

TOXIC EFFECTS :: Behavioral - excitement Behavioral - withdrawal Skin and Appendages - dermatitis, other (after systemic exposure)

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1500 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Behavioral - muscle weakness Lungs, Thorax, or Respiration - dyspnea

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1098 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 22709 mg/kg/36W-I

TOXIC EFFECTS :: Nutritional and Gross Metabolic - changes in metals, not otherwise specified

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 8190 mg/kg/26W-I

TOXIC EFFECTS :: Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Nutritional and Gross Metabolic - changes in metals, not otherwise specified

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 105 gm/kg/10W-I

TOXIC EFFECTS :: Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Nutritional and Gross Metabolic - changes in metals, not otherwise specified Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 10500 mg/kg/10W-I

TOXIC EFFECTS :: Blood - pigmented or nucleated red blood cells Nutritional and Gross Metabolic - changes in metals, not otherwise specified Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 2730 mg/kg/26W-I

TOXIC EFFECTS :: Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 28 gm/kg

SEX/DURATION :: female 26 week(s) pre-mating - 21 day(s) post-birth

TOXIC EFFECTS :: Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 750 mg/kg

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - other developmental abnormalities

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Human Lymphocyte

DOSE/DURATION :: 1 mmol/L

REFERENCE :: CYGEDX Cytology and Genetics (English Translation). Translation of TGANAK. (Allerton Press Inc., 150 Fifth Ave., New York, NY 10011) V.8- 1974- Volume(issue)/page/year: 8(4),31,1974

2,3-二巯基丙磺酸钠安全信息

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S24/25

[ WGK德国 ]:
3

[ RTECS号 ]:
TZ6420000

[ 海关编码 ]:
2930909090

2,3-二巯基丙磺酸钠海关

[ 海关编码 ]: 2930909090

[ 中文概述 ]:
2930909090. 其他有机硫化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%