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苯甲地那铵

苯甲地那铵用途

Denatonium是已知的最苦的化合物, 常用作厌恶剂 (苦味剂),以防止不适当的摄取, 用在工业酒精, 防冻液, 咬指甲癖预防, 呼吸器面罩配合测试, 动物驱虫剂, 液体皂和洗发水。

苯甲地那铵名称

[ CAS 号 ]:
3734-33-6

[ 中文名 ]:
苯甲地那铵

[ 英文名 ]:
denatonium benzoate

[中文别名 ]:

[英文别名 ]:

denatonium benzoate
EINECS 223-095-2
MFCD00031578
Denatonium (benzoate)

苯甲地那铵生物活性

[ 描述 ]:

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 其他

[相关活性小分子]

苯甲地那铵物理化学性质

[ 熔点 ]:
164-168 °C(lit.)

[ 分子式 ]:
C₂₈H₃₄N₂O₃

[ 分子量 ]:
446.581

[ 精确质量 ]:
446.256958

[ PSA ]:
69.23000

[ LogP ]:
4.42180

[ 外观性状 ]:
白色结晶

[ 储存条件 ]:
存放于惰性气体之中;避免湿气 (吸湿)

[ 稳定性 ]:
Stable. Incompatible with strong oxidizing agents.

[ 水溶解性 ]:
methanol: 50 mg/mL, clear, colorless

苯甲地那铵MSDS

详细MSDS(安全技术说明书)

苯甲地那铵毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BO6650000

CHEMICAL NAME :: Ammonium, benzyldiethyl((2,6-xylylcarbamoyl)methyl)-, benzoate

CAS REGISTRY NUMBER :: 3734-33-6

LAST UPDATED :: 199701

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C21-H29-N2-O.C7-H5-O2

MOLECULAR WEIGHT :: 446.64

WISWESSER LINE NOTATION :: 1R C1 BMV1K2&2&1R &OVR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 584 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - ataxia

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB81-139339

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 508 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - ataxia

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB81-139339 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1737 No. of Facilities: 989 (estimated) No. of Industries: 5 No. of Occupations: 9 No. of Employees: 10902 (estimated) No. of Female Employees: 7446 (estimated)

苯甲地那铵安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H315-H319-H335

[ 警示性声明 ]:
P301 + P312 + P330-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn:Harmful

[ 风险声明 (欧洲) ]:
R22;R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
2

[ RTECS号 ]:
BO6650000

[ 海关编码 ]:
29242995

苯甲地那铵海关

[ 海关编码 ]: 2924299090

[ 中文概述 ]:
2924299090. 其他环酰胺（包括环氨基甲酸酯）（包括其衍生物以及他们的盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 包装

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

苯甲地那铵文献

Enhancing perception of contaminated food through acid-mediated modulation of taste neuron responses.

Curr. Biol. 24(17) , 1969-77, (2014)

Natural foods contain not only nutrients, but also nonnutritious and potentially harmful chemicals. Thus, animals need to evaluate food content in order to make adequate feeding decisions.Here, we inv...

Vismodegib, an antagonist of hedgehog signaling, directly alters taste molecular signaling in taste buds.

Cancer Med. 4(2) , 245-52, (2015)

Vismodegib, a highly selective inhibitor of hedgehog (Hh) pathway, is an approved treatment for basal-cell carcinoma. Patients on treatment with vismodegib often report profound alterations in taste s...

A new dopaminergic nigro-olfactory projection.

Acta Neuropathol. 130 , 333-48, (2015)

Parkinson disease (PD) is a neurodegenerative disorder characterized by massive loss of midbrain dopaminergic neurons. Whereas onset of motor impairments reflects a rather advanced stage of the disord...

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