米洛沙星

米洛沙星名称

[ CAS 号 ]:
37065-29-5

[ 中文名 ]:
米洛沙星

[ 英文名 ]:
miloxacin

[英文别名 ]:

米洛沙星物理化学性质

[ 密度 ]:
1.6±0.1 g/cm3

[ 沸点 ]:
460.9±55.0 °C at 760 mmHg

[ 熔点 ]:
264° (dec)

[ 分子式 ]:
C12H9NO6

[ 分子量 ]:
263.203

[ 闪点 ]:
232.5±31.5 °C

[ 精确质量 ]:
263.042999

[ PSA ]:
86.99000

[ LogP ]:
1.34

[ 蒸汽压 ]:
0.0±1.2 mmHg at 25°C

[ 折射率 ]:
1.689

米洛沙星毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
JI5060000
CHEMICAL NAME :
1,3-Dioxolo(4,5-g)quinoline-7-carboxylic acid, 5,8-dihydro-5-methoxy-8-oxo-
CAS REGISTRY NUMBER :
37065-29-5
LAST UPDATED :
199612
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C12-H9-N-O6
MOLECULAR WEIGHT :
263.22
WISWESSER LINE NOTATION :
T C566 DO FO JN MV EHJ JO1 LVQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
36400 mg/kg/26W-I
TOXIC EFFECTS :
Liver - changes in liver weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Related to Chronic Data - changes in uterine weight
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
413 mg/kg
SEX/DURATION :
female 7-17 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - musculoskeletal system
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
1650 mg/kg
SEX/DURATION :
female 7-17 day(s) after conception
TOXIC EFFECTS :
Reproductive - Maternal Effects - parturition
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
3300 mg/kg
SEX/DURATION :
female 7-17 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
8100 mg/kg
SEX/DURATION :
female 17-22 day(s) after conception lactating female 21 day(s) post-birth
TOXIC EFFECTS :
Reproductive - Maternal Effects - parturition Reproductive - Effects on Newborn - weaning or lactation index (e.g., # alive at weaning per # alive at day 4) Reproductive - Effects on Newborn - physical

MUTATION DATA

TYPE OF TEST :
DNA inhibition
TEST SYSTEM :
Microorganism - not otherwise specified
DOSE/DURATION :
140 ug/L
REFERENCE :
AMACCQ Antimicrobial Agents and Chemotherapy. (American Soc. for Microbiology, 1913 I St., NW, Washington, DC 20006) V.1- 1972- Volume(issue)/page/year: 17,763,1980

米洛沙星安全信息

[ 海关编码 ]:
2934999090

米洛沙星合成路线

米洛沙星上下游产品

米洛沙星海关

[ 海关编码 ]: 2934999090

[ 中文概述 ]:
2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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