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色氨

色氨用途

Tryptamine(盐酸盐)是一种生物化学试剂,可作为生物材料或有机化合物用于生命科学相关研究。

色氨名称

[ CAS 号 ]:
343-94-2

[ 中文名 ]:
色胺盐酸盐

[ 英文名 ]:
2-(1h-indol-3-yl)ethanaminhydrochlorid

[中文别名 ]:

[英文别名 ]:

triptamine hydrochloride
3-(2-Aminoethyl)indole Hydrochloride
Indole, 3- (2-aminoethyl)-, monohydrochloride
serotonin hydrochloride
TryptaMine Hydrochloride
Indole-3-ethylamine hydrochloride
2-(1H-Indol-3-yl)éthanamine chlorhydrate
2-(1H-Indol-3-yl)ethanamine hydrochloride
MFCD00012682
1H-Indole-3-ethanamine, hydrochloride (1:1)

色氨生物活性

[ 描述 ]:

Tryptamine(盐酸盐)是一种生物化学试剂,可作为生物材料或有机化合物用于生命科学相关研究。

[ 相关类别 ]:

研究领域 >> 其他

色氨物理化学性质

[ 密度 ]:
1.157g/cm3

[ 沸点 ]:
378.8ºC at 760mmHg

[ 熔点 ]:
253-255 °C(lit.)

[ 分子式 ]:
C₁₀H₁₃ClN₂

[ 分子量 ]:
196.677

[ 闪点 ]:
187.7ºC

[ 精确质量 ]:
196.076721

[ PSA ]:
41.81000

[ LogP ]:
3.17140

[ 外观性状 ]:
固体;White to Orange to Green powder to crystal

[ 储存条件 ]:
库房通风低温干燥

[ 水溶解性 ]:
水溶性：可溶；水溶解度：64 g/l 20 °C

色氨MSDS

色氨毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NL4375000

CHEMICAL NAME :: Indole, 3-(2-aminoethyl)-, monohydrochloride

CAS REGISTRY NUMBER :: 343-94-2

LAST UPDATED :: 199701

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C10-H12-N2.Cl-H

MOLECULAR WEIGHT :: 196.70

WISWESSER LINE NOTATION :: T56 BMJ D2Z &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1300 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPMRAB Japanese Journal of Medical Sciences, Part 4: Pharmacology. (Tokyo, Japan) V.1-16, 1926-43. For publisher information, see JJPAAZ. Volume(issue)/page/year: 2,77,1927

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 197 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 94,1620,1974

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 504 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 33,180,1970

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 109 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 23,43,1964

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPMRAB Japanese Journal of Medical Sciences, Part 4: Pharmacology. (Tokyo, Japan) V.1-16, 1926-43. For publisher information, see JJPAAZ. Volume(issue)/page/year: 2,77,1927 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4652 No. of Facilities: 10 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 34 (estimated) No. of Female Employees: 3 (estimated)

色氨安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xn: Harmful;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S22-S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
NL4375000

[ 海关编码 ]:
2942000000

色氨合成路线

色氨上下游产品

色氨上游产品

色氨下游产品

色氨海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

色氨文献

Chemical genetics reveals a complex functional ground state of neural stem cells.

Nat. Chem. Biol. 3(5) , 268-273, (2007)

The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain canc...

New procedure of selected biogenic amines determination in wine samples by HPLC.

Anal. Chim. Acta 834 , 58-66, (2014)

A new procedure for determination of biogenic amines (BA): histamine, phenethylamine, tyramine and tryptamine, based on the derivatization reaction with 2-chloro-1,3-dinitro-5-(trifluoromethyl)-benzen...

Enantioselective formal synthesis of ent-rhynchophylline and ent-isorhynchophylline.

Chem. Commun. (Camb.) 49(19) , 1954-6, (2013)

Starting from (S)-tryptophanol, a formal synthesis of ent-rhynchophylline and ent-isorhynchophylline, involving stereoselective cyclocondensation, spirocyclization, and alkylation reactions, and the f...

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色氨