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盐酸吗啉胍

盐酸吗啉胍用途

Moroxydine盐酸盐是抗流感病毒化合物。

盐酸吗啉胍名称

[ CAS 号 ]:
3160-91-6

[ 中文名 ]:
盐酸吗啉胍

[ 英文名 ]:
Moroxydine (hydrochloride)

[中文别名 ]:

[英文别名 ]:

Moroxydine (hydrochloride)
4-Morpholinecarboximidoylguanidine Hydrochloride
abobhydrochloride
Moroxydine hydrochlorid
assur
Moroxydine hydrochloride
N,N-oxapentamethylenebiguanide hydrochloride
virusmin
virustat
N1-morpholinobiguanidine hydrochloride

盐酸吗啉胍生物活性

[ 描述 ]:

Moroxydine盐酸盐是抗流感病毒化合物。

[ 相关类别 ]:

信号通路 >> 抗感染 >> 流感病毒

研究领域 >> 感染

[参考文献]

[1]. Sheppard, S., Moroxydine: the story of a mislaid antiviral. Acta Derm Venereol Suppl (Stockh), 1994. 183: p. 1-9.

[2]. Moore, Malcolm. "China: All children to be given drug tests after schools caught medicating pupils". The Age. Retrieved 2014-03-20.

[相关活性小分子]

盐酸吗啉胍物理化学性质

[ 沸点 ]:
327ºC at 760 mmHg

[ 熔点 ]:
211-214ºC(lit.)

[ 分子式 ]:
C₆H₁₄ClN₅O

[ 分子量 ]:
207.661

[ 闪点 ]:
151.6ºC

[ 精确质量 ]:
207.088684

[ PSA ]:
98.22000

[ LogP ]:
0.76700

[ 外观性状 ]:
白色结晶粉末

[ 储存条件 ]:
室温

[ 水溶解性 ]:
水溶性：可溶

盐酸吗啉胍MSDS

详细MSDS(安全技术说明书)

盐酸吗啉胍毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QD9815000

CHEMICAL NAME :: 4-Morpholinecarboxamidine, N-amidino-, monohydrochloride

CAS REGISTRY NUMBER :: 3160-91-6

LAST UPDATED :: 199501

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C6-H13-N5-O.Cl-H

MOLECULAR WEIGHT :: 207.70

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >6250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 2,474,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1750 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JAJAAA Journal of Antibiotics, Series A. (Tokyo, Japan) V.6-20, 1953-67. For publisher information, see JANTAJ. Volume(issue)/page/year: 18,196,1965

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 2,474,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 325 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 2,474,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 2,474,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 2,474,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 2,474,1960

盐酸吗啉胍安全信息

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
26-37/39

[ WGK德国 ]:
3

[ RTECS号 ]:
QD9815000

[ 海关编码 ]:
2934999090

盐酸吗啉胍合成路线

详细合成路线

盐酸吗啉胍上下游产品

盐酸吗啉胍上游产品

盐酸吗啉胍下游产品

盐酸吗啉胍海关

[ 海关编码 ]: 2934999090

[ 中文概述 ]:
2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%