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1,3-环己二甲胺

1,3-环己二甲胺名称

[ CAS 号 ]:
2579-20-6

[ 中文名 ]:
1,3-环己二甲胺

[ 英文名 ]:
1,3-Cyclohexanediyldimethanamine

[中文别名 ]:

[英文别名 ]:

1,3-Di(aminomethyl)cyclohexane
L6TJ A1Z C1Z
1,3-Cyclohexanebis(methylamine)
Kodak silver halide solvent HS-103
EINECS 219-941-5
1,3-Bis(aminomethyl)cyclohexane
1,3-Cyclohexanedimethanamine
1,3-Cyclohexanediyldimethanamine
Hexahydro-m-xylylenediamine
MFCD00001522

1,3-环己二甲胺物理化学性质

[ 密度 ]:
0.9±0.1 g/cm3

[ 沸点 ]:
219.9±8.0 °C at 760 mmHg

[ 熔点 ]:
-70 °C

[ 分子式 ]:
C₈H₁₈N₂

[ 分子量 ]:
142.242

[ 闪点 ]:
106.1±0.0 °C

[ 精确质量 ]:
142.147003

[ PSA ]:
52.04000

[ LogP ]:
0.47

[ 蒸汽压 ]:
0.1±0.4 mmHg at 25°C

[ 折射率 ]:
1.478

[ 储存条件 ]:
2-8°C

[ 水溶解性 ]:
可溶

1,3-环己二甲胺MSDS

1,3-环己二甲胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GU7000000

CHEMICAL NAME :: Cyclohexane, 1,3-bis(aminomethyl)-

CAS REGISTRY NUMBER :: 2579-20-6

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C8-H18-N2

MOLECULAR WEIGHT :: 142.28

WISWESSER LINE NOTATION :: L6TJ A1Z C1Z

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 880 mg/kg

TOXIC EFFECTS :: Gastrointestinal - other changes

REFERENCE :: HURC** Huntingdon Research Center Reports. (Box 527, Brooklandville, MD 21022) Volume(issue)/page/year: -,-,1973

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: KODAK* Kodak Company Reports. (343 State St., Rochester, NY 14650) Volume(issue)/page/year: 21MAY1971

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 25 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: KODAK* Kodak Company Reports. (343 State St., Rochester, NY 14650) Volume(issue)/page/year: 21MAY1971

1,3-环己二甲胺安全信息

[ 符号 ]:

GHS05, GHS07

[ 信号词 ]:
Danger

[ 危害声明 ]:
H302 + H312-H314-H412

[ 警示性声明 ]:
P273-P280-P305 + P351 + P338-P310

[ 个人防护装备 ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
C

[ 风险声明 (欧洲) ]:
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . R34:Causes burns. R22:Harmful if swallowed.

[ 安全声明 (欧洲) ]:
S26-S27-S28-S36/37/39-S45-S25

[ 危险品运输编码 ]:
UN 2735 8/PG 2

[ WGK德国 ]:
3

[ RTECS号 ]:
GU7000000

[ 包装等级 ]:
I

[ 危险类别 ]:
8

[ 海关编码 ]:
2921300090

1,3-环己二甲胺合成路线

1,3-环己二甲胺海关

[ 海关编码 ]: 2921300090

[ 中文概述 ]:
2921300090 其他环（烷，烯，萜烯）单胺或多胺（包括其衍生物及它们的盐）. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2921300090 other cyclanic, cyclenic or cyclotherpenic mono- or polyamines, and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

1,3-环己二甲胺文献

Retrograde transport of protein toxins under conditions of COPI dysfunction.

Biochim. Biophys. Acta 1589(2) , 124-39, (2002)

Retrograde transport dependent on coat protein I (COPI) was impaired using two different approaches and the effects on the retrograde transport of protein toxins were investigated. One approach was to...

Use of aminoglycoside antibiotics and related compounds to study ADP-ribosylation factor (ARF)/coatomer function in Golgi traffic.

Meth. Enzymol. 329 , 372-9, (2001)

Inhibition of secretion by 1,3-Cyclohexanebis(methylamine), a dibasic compound that interferes with coatomer function.

Mol. Biol. Cell 10(4) , 921-33, (1999)

We noted previously that certain aminoglycoside antibiotics inhibit the binding of coatomer to Golgi membranes in vitro. The inhibition is mediated in part by two primary amino groups present at the 1...

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