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雷复尼特

雷复尼特用途

Rafoxanide是一具抗寄生虫活性水杨酰苯胺化合物。

雷复尼特名称

[ CAS 号 ]:
22662-39-1

[ 中文名 ]:
雷复沙奈

[ 英文名 ]:
Rafoxanide

[中文别名 ]:

[英文别名 ]:

EINECS 245-148-9
MFCD00682899
Rafoxanide

雷复尼特生物活性

[ 描述 ]:

Rafoxanide是一具抗寄生虫活性水杨酰苯胺化合物。

[ 相关类别 ]:

信号通路 >> 抗感染 >> 寄生物

研究领域 >> 感染

[相关活性小分子]

雷复尼特物理化学性质

[ 密度 ]:
2.0±0.1 g/cm3

[ 沸点 ]:
526.6±50.0 °C at 760 mmHg

[ 熔点 ]:
169ºC

[ 分子式 ]:
C₁₉H₁₁Cl₂I₂NO₃

[ 分子量 ]:
626.010

[ 闪点 ]:
272.3±30.1 °C

[ 精确质量 ]:
624.820496

[ PSA ]:
58.56000

[ LogP ]:
9.36

[ 外观性状 ]:
淡黄色棕色溶液

[ 蒸汽压 ]:
0.0±1.4 mmHg at 25°C

[ 折射率 ]:
1.753

[ 储存条件 ]:
0-6°C

雷复尼特MSDS

详细MSDS(安全技术说明书)

雷复尼特毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VN7870000

CHEMICAL NAME :: Salicylanilide, 3'-chloro-4'-(p-chlorophenoxy)-3,5-diiodo-

CAS REGISTRY NUMBER :: 22662-39-1

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C19-H11-Cl2-I2-N-O3

MOLECULAR WEIGHT :: 626.01

WISWESSER LINE NOTATION :: QR BI DI FVMR CG DOR DG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Mammal - cattle

DOSE/DURATION :: 80 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: REMVAY Revue d'Elevage et de Medicine Veterinaire des Pays Tropicaux. (Editions Vigot, 23 rue de l'Ecole-de-Medecine, F-75006 Paris, France) V.1- 1947- Volume(issue)/page/year: 29,31,1976

雷复尼特安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ RTECS号 ]:
VN7870000

[ 海关编码 ]:
2924299090

雷复尼特制备

雷复尼特海关

[ 海关编码 ]: 2924299090

[ 中文概述 ]:
2924299090. 其他环酰胺（包括环氨基甲酸酯）（包括其衍生物以及他们的盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 包装

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

雷复尼特文献

The Hymenolepis diminuta-golden hamster (Mesocricetus auratus) model for the evaluation of gastrointestinal anticestode activity.

J. Parasitol. 90(4) , 898-9, (2004)

A novel laboratory anticestode assay was developed using Hymenolepis diminuta in the hamster. The commercial anticestode compounds, praziquantel, bunamidine, and niclosamide were active against patent...

An improved thyroid hormone reporter assay to determine the thyroid hormone-like activity of amiodarone, bithionol, closantel and rafoxanide.

Toxicol. Lett. 208(1) , 30-5, (2012)

A number of environmental chemicals have been reported to exhibit thyroid hormone-like activity. Since thyroid hormones play a crucial role in development, it is important to identify chemicals in the...

Screening of closantel and rafoxanide in animal muscles by HPLC with fluorescence detection and confirmation using MS.

J. Sep. Sci. 33(2) , 206-11, (2010)

A sensitive and selective LC-FLD method was described for determination of closantel and rafoxanide in bovine and ovine muscles. Bovine and ovine muscles were extracted with ACN and acetone mixture (8...

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