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2,2'-二硫双(5-硝基吡啶)

2,2'-二硫双(5-硝基吡啶)用途

【用途一】
检测硫醇的选择性试剂，叶绿体偶联因子I的ATP酶的抑制剂。

2,2'-二硫双(5-硝基吡啶)名称

[ CAS 号 ]:
2127-10-8

[ 中文名 ]:
2,2'-二硫双(5-硝基吡啶)

[ 英文名 ]:
2,2'-dithiobis(5-nitropyridine)

[中文别名 ]:

2,2’-二硫双(5-硝基吡啶)

[英文别名 ]:

Bis(5-nitro-2-pyridyl) disulfide,DTNP
MFCD00006453
DTNP
1,2-bis(5-nitropyridin-2-yl)disulfane
2,2'-DIMETHYL-4,4'-BIPHENYLDIOL
Bis(5-nitro-2-pyridyl) disulfide
5,5'-dinitro-2,2'-dithiodipyridine
EINECS 218-344-7
bis(5-nitro-pyridin-2-yl)-disulfide
2,2'-Dithiobis(5-nitropyridine)

2,2'-二硫双(5-硝基吡啶)物理化学性质

[ 密度 ]:
1.65g/cm3

[ 沸点 ]:
514.2ºC at 760mmHg

[ 熔点 ]:
155-157 °C(lit.)

[ 分子式 ]:
C₁₀H₆N₄O₄S₂

[ 分子量 ]:
310.30900

[ 闪点 ]:
264.8ºC

[ 精确质量 ]:
309.98300

[ PSA ]:
168.02000

[ LogP ]:
4.13880

[ 蒸汽压 ]:
3.58E-10mmHg at 25°C

[ 折射率 ]:
1.733

[ 储存条件 ]:
Store at RT.

2,2'-二硫双(5-硝基吡啶)MSDS

2,2'-二硫双(5-硝基吡啶)毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UT2964000

CHEMICAL NAME :: Pyridine, 2,2'-dithiobis(5-nitro-

CAS REGISTRY NUMBER :: 2127-10-8

BEILSTEIN REFERENCE NO. :: 0305413

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C10-H6-N4-O4-S2

MOLECULAR WEIGHT :: 310.32

WISWESSER LINE NOTATION :: T6NJ ENW BSS- BT6NJ ENW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 50 ug/plate

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 67,123,1979

2,2'-二硫双(5-硝基吡啶)安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
36/37/38

[ 安全声明 (欧洲) ]:
S36/37/39

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
UT2964000

[ 海关编码 ]:
2933399090

2,2'-二硫双(5-硝基吡啶)合成路线

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2,2'-二硫双(5-硝基吡啶)海关

[ 海关编码 ]: 2933399090

[ 中文概述 ]:
2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

2,2'-二硫双(5-硝基吡啶)文献

Heterologous expression of NaV1.9 chimeras in various cell systems.

Pflugers Arch. 467 , 2423-35, (2015)

SCN11A encodes the voltage-gated sodium channel NaV1.9, which deviates most strongly from the other eight NaV channels expressed in mammals. It is characterized by resistance to the prototypic NaV cha...

Disinactivation of N-type inactivation of voltage-gated K channels by an erbstatin analogue.

J. Biol. Chem. 279(28) , 29226-30, (2004)

In some A-type voltage-gated K channels, rapid inactivation is achieved through the binding of an N-terminal domain of the pore-forming alpha-subunit or an associated beta-subunit to a cytoplasmic acc...

2,2'-Dithiobis(5-nitropyridine) (DTNP) as an effective and gentle deprotectant for common cysteine protecting groups.

J. Pept. Sci. 18(1) , 1-9, (2012)

Of all the commercially available amino acid derivatives for solid phase peptide synthesis, none has a greater abundance of side-chain protection diversity than cysteine. The high reactivity of the cy...

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