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6-硝基藜芦醛

6-硝基藜芦醛用途

DMNB(6-硝基藜芦醛)是一种前体,可用于合成添加了6-[18F]氟-L-多巴(6-FDOPA)的no载体。没有添加载体(NCA)的6-[18F]氟-L-多巴(6-FDOPA)常规用于多巴胺能系统的PET研究[1]。

6-硝基藜芦醛名称

[ CAS 号 ]:
20357-25-9

[ 中文名 ]:
6-硝基藜芦醛

[ 英文名 ]:
6-Nitroveratraldehyde

[中文别名 ]:

[英文别名 ]:

4,5-dimethoxy-2-nitro-benzaldehyde
Benzaldehyde,4,5-dimethoxy-2-nitro
3,4-Dimethoxy-6-nitrobenzaldehyde
6-Nitroveratraldehyde
2-nitro-4,5-dimethoxybenzaldehyde
DNA-Dependent Protein Kinase Inhibitor
DMNB
EINECS 243-762-1
MFCD00007134
DNA-PK Inhibitor

6-硝基藜芦醛生物活性

[ 描述 ]:

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 神经疾病

[参考文献]

[1]. Zhang Lan, et al. Preparation of 6-[¹⁸F]fluoro-L-DOPA and its biodistribution in normal and unilateral PD model rats. Nuclear Science and Techniques, 13(4), 244-250.

[2]. Reddy GN, et al. Quality assurance and quality control methods for animal and human applications of no-carrier-added 6-[18F]fluorodopa for PET investigations of dopaminergic systems. Appl Radiat Isot. 1993;44(7):993-998.

6-硝基藜芦醛物理化学性质

[ 密度 ]:
1.312 g/cm3

[ 沸点 ]:
390.8ºC at 760 mmHg

[ 熔点 ]:
133.2-134.5 °C

[ 分子式 ]:
C₉H₉NO₅

[ 分子量 ]:
211.17100

[ 闪点 ]:
194.3ºC

[ 精确质量 ]:
211.04800

[ PSA ]:
81.35000

[ LogP ]:
1.94770

[ 外观性状 ]:
黄色固体

[ 蒸汽压 ]:
2.59E-06mmHg at 25°C

[ 折射率 ]:
1.571

[ 储存条件 ]:
2-8°C

[ 水溶解性 ]:
DMSO: 22 mg/mL

6-硝基藜芦醛MSDS

详细MSDS(安全技术说明书)

6-硝基藜芦醛安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 安全声明 (欧洲) ]:
S24/25

[ 危险品运输编码 ]:
UN 2811 6.1/PG 3

[ WGK德国 ]:
3

[ RTECS号 ]:
GY8410000

[ 海关编码 ]:
2913000090

6-硝基藜芦醛上下游产品

6-硝基藜芦醛上游产品

6-硝基藜芦醛下游产品

6-硝基藜芦醛海关

[ 海关编码 ]: 2913000090

[ 中文概述 ]:
2913000090 品目2912所列产品的其他衍生物〔指卤化,磺化,硝化或亚硝化的衍生物〕. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:5.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
HS: 2913000090 halogenated, sulphonated, nitrated or nitrosated derivatives of products of heading 2912 Educational tariff:17.0% Tax rebate rate:9.0% Regulatory conditions:none Most favored nation tariff:5.5% General tariff:30.0%

6-硝基藜芦醛文献

An improved synthesis of no-carrier-added (NCA) 6-[¹⁸ F] Fluoro-l-DOPA and its remote routine production for PET investigations of dopaminergic systems. Reddy GN, et al.

Appl. Radiat. Isot. 44(4) , 645-49, (1993)

o-Nitroaryl-bis (5-methylfur-2-yl) methanes as Versatile Synthons for the Synthesis of Nitrogen-Containing Heterocycles. Butin AV, et al.

Molecules 2(4) , 62-8, (1997)

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