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赛草青

赛草青用途

Chlorthiamid 是一种广谱除草剂。Chlorthiamid 是一种嗅觉毒物,在小鼠嗅粘膜中具有高体内共价结合。

赛草青名称

[ CAS 号 ]:
1918-13-4

[ 中文名 ]:
氯硫酰草胺

[ 英文名 ]:
Chlorthiamid

[中文别名 ]:

[英文别名 ]:

2,6-dichlorobenzothioamide
2,6-dichlorothiobenzamide
Chlorothiamide
Prefix
Chlorthioamide
MFCD00053523
2,6-dichlorobenzenecarbothioamide
2,5-DICHLOROBENZYL BROMIDE
DCBN
2,6 dichlorothiobenzamide

赛草青生物活性

[ 描述 ]:

Chlorthiamid 是一种广谱除草剂。Chlorthiamid 是一种嗅觉毒物,在小鼠嗅粘膜中具有高体内共价结合。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. C Eriksson, et al. Effects of the herbicide chlorthiamid on the olfactory mucosa. Toxicol Lett. 1995 Apr;76(3):203-8.

赛草青物理化学性质

[ 密度 ]:
1.473g/cm3

[ 沸点 ]:
320.6ºC at 760mmHg

[ 熔点 ]:
151-152°C

[ 分子式 ]:
C₇H₅Cl₂NS

[ 分子量 ]:
206.09200

[ 闪点 ]:
>100 °C

[ 精确质量 ]:
204.95200

[ PSA ]:
58.11000

[ LogP ]:
3.32790

[ 蒸汽压 ]:
0.000314mmHg at 25°C

[ 折射率 ]:
1.669

[ 储存条件 ]:
库房通风低温干燥,与食品原料分开储运

赛草青MSDS

赛草青毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CV3850000

CHEMICAL NAME :: Benzamide, 2,6-dichlorothio-

CAS REGISTRY NUMBER :: 1918-13-4

LAST UPDATED :: 199712

DATA ITEMS CITED :: 13

MOLECULAR FORMULA :: C7-H5-Cl2-N-S

MOLECULAR WEIGHT :: 206.09

WISWESSER LINE NOTATION :: SUYZR BG FG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 757 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Behavioral - general anesthetic

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 242 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Behavioral - sleep

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Gastrointestinal - nausea or vomiting

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 300 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - domestic

DOSE/DURATION :: 125 mg/kg

TOXIC EFFECTS :: Behavioral - sleep

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 16800 mg/kg/4W-C

TOXIC EFFECTS :: Liver - changes in liver weight Blood - changes in bone marrow (not otherwise specified) Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 173 mg/kg/13W-C

TOXIC EFFECTS :: Liver - changes in liver weight

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 3150 mg/kg/21D-I

TOXIC EFFECTS :: Nutritional and Gross Metabolic - weight loss or decreased weight gain

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 500 mg/kg

REFERENCE :: CYGEDX Cytology and Genetics (English Translation). Translation of TGANAK. (Allerton Press Inc., 150 Fifth Ave., New York, NY 10011) V.8- 1974- Volume(issue)/page/year: 14(6),38,1980

赛草青安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn: Harmful;

[ 风险声明 (欧洲) ]:
R22

[ 安全声明 (欧洲) ]:
S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ RTECS号 ]:
CV3850000

[ 海关编码 ]:
2930909056

赛草青合成路线

赛草青上下游产品

赛草青上游产品

赛草青下游产品

赛草青海关

[ 海关编码 ]: 2930909056

[ 中文概述 ]:
2930909056 烯草酮、磺草酮、嗪草酸甲酯、硝磺草酮等〔包括苯氟磺胺、甲磺乐灵、氯硫酰草胺、脱叶磷〕。监管条件:S(进出口农药登记证明)。增值税率:17.0%。退税率:9.0%。最低关税:6.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ 监管条件 ]: S.进出口农药登记证明

[ Summary ]:
2930909056 2,6-dichlorobenzothioamide。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:30.0%

赛草青文献

Toxicity of 2,6-dichlorothiobenzamide (chlorthiamid) and 2,6-dichlorobenzamide in the olfactory nasal mucosa of mice.

Fundam. Appl. Toxicol. 17(1) , 92-102, (1991)

The toxic effects of the herbicide chlorthiamid (2,6-dichlorothiobenzamide) and its major environmental metabolite 2,6-dichlorobenzamide (DCBA) were examined in the nasal passages of C57Bl mice follow...

Metabolism of 2,6-dichlorobenzonitrile, 2,6-dichlorothiobenzamide in rodents and goats.

Xenobiotica 18(9) , 1063-75, (1988)

1. Twelve 14C-labelled metabolites were isolated from either urine or bile from either rats (11 metabolites) or goats (7 metabolites) given single oral doses of 2,6-dichlorobenzo[14C]nitrile (DCBN). F...

Effects of the herbicide chlorthiamid on the olfactory mucosa.

Toxicol. Lett. 76(3) , 203-8, (1995)

Chlorthiamid (2,6-dichlorothiobenzamide) and its major metabolite 2,6-dichlorobenzonitrile are olfactory toxicants with a high in vivo covalent binding in the olfactory mucosa of mice. This study show...

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赛草青