二苯乙醇酸莨菪酯盐酸盐

二苯乙醇酸莨菪酯盐酸盐名称

[ CAS 号 ]:
1674-94-8

[ 中文名 ]:
二苯乙醇酸莨菪酯盐酸盐

[ 英文名 ]:
endo-8-Methyl-8-azabicyclo[3.2.1]octan-3-yl 2-hydroxy-2,2-diphenylacetate hydrochloride

[英文别名 ]:

二苯乙醇酸莨菪酯盐酸盐物理化学性质

[ 沸点 ]:
444.7ºC at 760mmHg

[ 分子式 ]:
C₂₂H₂₆ClNO₃

[ 分子量 ]:
387.90000

[ 闪点 ]:
222.7ºC

[ 精确质量 ]:
387.16000

[ PSA ]:
49.77000

[ LogP ]:
3.83080

[ 蒸汽压 ]:
1.09E-08mmHg at 25°C

二苯乙醇酸莨菪酯盐酸盐毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YM4151000

CHEMICAL NAME :: 1-alpha-H,5-alpha-H-Tropan-3-alpha-ol, benzilate (ester), hydrochloride

CAS REGISTRY NUMBER :: 1674-94-8

LAST UPDATED :: 199510

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C22-H25-N-O3.Cl-H

MOLECULAR WEIGHT :: 387.94

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 92580 ug/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Behavioral - excitement

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 120,160,1959

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 130 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 7,217,1957

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 13680 ug/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Behavioral - excitement

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 120,160,1959

二苯乙醇酸莨菪酯盐酸盐安全信息

[ 海关编码 ]:
2933990090

二苯乙醇酸莨菪酯盐酸盐海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%