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5'-二磷酸鸟嘌呤核苷-岩藻糖二钠盐

5'-二磷酸鸟嘌呤核苷-岩藻糖二钠盐用途

GDP-L-岩藻糖是一种核苷酸糖,它是岩藻糖寡糖生物合成的关键底物,为寡糖提供岩藻糖部分。GDP-L-岩藻糖的形成通过两种途径,主要从头代谢途径和次要补救代谢途径[1]。

5'-二磷酸鸟嘌呤核苷-岩藻糖二钠盐名称

[ CAS 号 ]:
15839-70-0

[ 中文名 ]:
5'-二磷酸鸟嘌呤核苷-岩藻糖二钠盐

[ 英文名 ]:
GDP-L-fucose disodium salt

[英文别名 ]:

GDP-β-L-FUCOSE, DISODIUM SALT
Guanosine 5'-diphospho-β-L-fucose disodium salt
Guanosine diphosphate fucose
GDP-L-fucose disodium salt

5'-二磷酸鸟嘌呤核苷-岩藻糖二钠盐生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 代谢疾病

[ 靶点 ]

Human Endogenous Metabolite

[参考文献]

[1]. Weiyang Wang, et al. Cell-free enzymatic synthesis of GDP-L-fucose from mannose. AMB Express. 2019 May 27;9(1):74.

5'-二磷酸鸟嘌呤核苷-岩藻糖二钠盐物理化学性质

[ 密度 ]:
2.4±0.1 g/cm3

[ 沸点 ]:
1006.6ºC at 760 mmHg

[ 分子式 ]:
C₁₆H₂₃N₅Na₂O₁₅P₂

[ 分子量 ]:
589.342

[ 闪点 ]:
562.6ºC

[ 精确质量 ]:
589.082214

[ PSA ]:
336.77000

[ LogP ]:
-2.95

[ 蒸汽压 ]:
0mmHg at 25°C

[ 折射率 ]:
1.869

5'-二磷酸鸟嘌呤核苷-岩藻糖二钠盐MSDS

详细MSDS(安全技术说明书)

5'-二磷酸鸟嘌呤核苷-岩藻糖二钠盐安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

5'-二磷酸鸟嘌呤核苷-岩藻糖二钠盐上下游产品

5'-二磷酸鸟嘌呤核苷-岩藻糖二钠盐上游产品

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5'-二磷酸鸟嘌呤核苷-岩藻糖二钠盐文献

Low glucose depletes glycan precursors, reduces site occupancy and galactosylation of a monoclonal antibody in CHO cell culture.

Biotechnol. J. 10 , 1051-66, (2015)

Controlled feeding of glucose has been employed previously to enhance the productivity of recombinant glycoproteins but there is a concern that low concentrations of glucose could limit the synthesis ...

Chemo-enzymatic supported synthesis of the 3-sulfated Lewis a pentasaccharide on a multimeric polyethylene glycol.

Carbohydr. Res. 343(5) , 970-6, (2008)

The 3-sulfated Lewis(a) pentasaccharide was synthesized on multimeric-based polyethylene glycol support. Coupling of O-(2,3,4,6-tetra-O-acetyl-beta-D-galactopyranosyl)-(1-->3)-4,6-di-O-acetyl-2-deoxy-...

Structures of NodZ α1,6-fucosyltransferase in complex with GDP and GDP-fucose.

Acta Crystallogr. D Biol. Crystallogr. 68 , 160-168, (2012)

Rhizobial NodZ α1,6-fucosyltransferase (α1,6-FucT) catalyzes the transfer of the fucose (Fuc) moiety from guanosine 5'-diphosphate-β-L-fucose to the reducing end of the chitin oligosaccharide core dur...

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