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氘代苊

氘代苊用途

Acecyclane-d10是氘标记的Acecyclane[1]。

氘代苊名称

[ CAS 号 ]:
15067-26-2

[ 中文名 ]:
苊-d10

[ 英文名 ]:
(2H10)-1,2-Dihydroacenaphthylene

[中文别名 ]:

氘代苊

[英文别名 ]:

Acenaphthene-d10
perdeuterioacenaphthene
Perdeuterioacenaphthen
MFCD00068265
d10-acenaphthene
(H)-1,2-Dihydroacenaphthylene
Acenaphthylene-d, 1,2-dihydro-d-
decadeuterio-acenaphthene
Acenaphthylene-d8,1,2-dihydro-d2
Deuteroacenaphthen

氘代苊生物活性

[ 描述 ]:

Acecyclane-d10是氘标记的Acecyclane[1]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[体外研究]

氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。重复使用因其可能影响药物的药代动力学和代谢谱而受到关注[1]。

[参考文献]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

氘代苊物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
279.0±0.0 °C at 760 mmHg

[ 熔点 ]:
95-97ºC(lit.)

[ 分子式 ]:
C₁₂D₁₀

[ 分子量 ]:
164.269

[ 闪点 ]:
135.3±9.7 °C

[ 精确质量 ]:
164.141022

[ LogP ]:
4.19

[ 蒸汽压 ]:
0.0±0.3 mmHg at 25°C

[ 折射率 ]:
1.692

[ 储存条件 ]:
0-6°C

氘代苊MSDS

氘代苊安全信息

[ 符号 ]:

GHS07, GHS09

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335-H410

[ 警示性声明 ]:
P261-P273-P305 + P351 + P338-P501

[ 靶器官 ]:
Blood, Central nervous system, Liver

[ 危害码 (欧洲) ]:
T: Toxic;Xi: Irritant;N: Dangerous for the environment;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
26-37/39-36/37-24/25-23-53-45-61-60

[ 危险品运输编码 ]:
UN 3077 9

[ WGK德国 ]:
3

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氘代苊文献

Concentrations, gas-particle partitioning, and seasonal variations of polycyclic aromatic hydrocarbons at four sites in Turkey.

Arch. Environ. Contam. Toxicol. 68(1) , 46-63, (2015)

Ambient air polycyclic aromatic hydrocarbon (PAH) samples were collected at traffic, residential, coastal, and semiurban sites in Bursa, Turkey, between June 2008 and June 2009. For the traffic, resid...

Experimental paradigm for in-laboratory proxy aquatic studies under conditions of static, non-flow-through chemical exposures.

Environ. Toxicol. Chem. 34 , 2796-802, (2015)

Endocrine-disrupting chemicals (EDCs) such as 17α-ethynylestradiol, 17β-estradiol, estrone, and para-nonylphenol have been measured in wastewater-treatment plant effluents, surface waters, sediments, ...

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氘代苊