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3-(联苯-4-基)-5-(4-叔丁基苯基)-4-苯基-4H-1,2,4-三唑

名称

[ CAS 号 ]:
150405-69-9

[ 中文名 ]:
3-(联苯-4-基)-5-(4-叔丁基苯基)-4-苯基-4H-1,2,4-三唑

[ 英文名 ]:
3-(Biphenyl-4-yl)-5-(4-tert-butylphenyl)-4-phenyl-4H-1,2,4-triazole

[中文别名 ]:

[英文别名 ]:

物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
611.5±58.0 °C at 760 mmHg

[ 熔点 ]:
231-235 â„ƒ

[ 分子式 ]:
C₃₀H₂₇N₃

[ 分子量 ]:
429.556

[ 闪点 ]:
323.6±32.3 °C

[ 精确质量 ]:
429.220490

[ PSA ]:
30.71000

[ LogP ]:
9.55

[ 蒸汽压 ]:
0.0±1.8 mmHg at 25°C

[ 折射率 ]:
1.615

安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ 危害码 (欧洲) ]:
Xn

[ 风险声明 (欧洲) ]:
22

[ 危险品运输编码 ]:
NONH for all modes of transport

文献

Inhibitory mechanism of FAT4 gene expression in response to actin dynamics during Src-induced carcinogenesis.

PLoS ONE 10(2) , e0118336, (2015)

Oncogenic transformation is characterized by morphological changes resulting from alterations in actin dynamics and adhesive activities. Emerging evidence suggests that the protocadherin FAT4 acts as ...

Molecular profiling and computational network analysis of TAZ-mediated mammary tumorigenesis identifies actionable therapeutic targets.

Oncotarget 5(23) , 12166-76, (2015)

Triple-negative breast cancer (TNBC) accounts for approximately 15-20% of all breast cancer (BC) cases and contributes disproportionately to BC mortality. TAZ, a key transducer of the Hippo pathway, h...

Characterization of TAZ domains important for the induction of breast cancer stem cell properties and tumorigenesis.

Cell Cycle 14(1) , 146-56, (2015)

The Hippo pathway is an evolutionarily conserved regulator of tissue growth and cell fate during development and regeneration. Conversely, deregulation of the Hippo pathway has been reported in severa...

更多文献

3-(联苯-4-基)-5-(4-叔丁基苯基)-4-苯基-4H-1,2,4-三唑

名称

物理化学性质

安全信息

文献

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